The San Francisco 49ers know their opponents on the 2021 NFL schedule.
49ers 2021 opponents set for 16-game season
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49ers' 2021 opponents finalized after early Week 17 action
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The San Francisco 49ers' 2021 season opponent list has been finalized following the early games from Week 17's action. The NFL will not announce the dates and times for next season's schedule until April or May. This season's schedule was released on May 7, 2020.
As it does...
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