The news isn't great for two of the 49ers' most important players on offense.
49ers George Kittle has sprained knee, Deebo Samuel suffers setback
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Kyle Shanahan: George Kittle suffered a knee sprain during 49ers-Cardinals, Deebo Samuel's setback, Brandon Aiyuk and Richie James injury updates
Kyle Shanahan: George Kittle suffered a knee sprain during 49ers-Cardinals, Deebo Samuel's setback, Brandon Aiyuk and Richie James injury updates
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