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The San Francisco 49ers entered the offseason motivated by February's Super Bowl defeat. Maybe that wasn't enough because the team gained some extra motivation the hard way on Sunday after the Arizona Cardinals pulled off the upset 24-20 win at Levi's Stadium. The loss forces San Francisco to play catchup with the rest of the division. It is the only NFC West squad that suffered a defeat during Week 1. The 49ers are back to work this week and beginning preparations for their two-game road trip to the East Coast, where they will face the New York Jets and New York Giants at MetLife Stadium in back-to-back weekends. The team's focus remains on the opponent

The San Francisco 49ers are placing cornerback Richard Sherman on short-term injured reserve, according to Mike Garafolo of NFL Network. That means missing at least the next three games. While Garafolo didn't have the specifics of the injury, merely noting that it was a "leg issue," his colleague, Ian Rapoport later reported that Sherman suffered a calf strain, which requires "a few weeks of rest and rehab." The #49ers are placing CB Richard Sherman on IR today, sources say. He'll be sidelined at least three weeks. Exact

The injuries just keep piling up for the San Francisco 49ers. Hot on the heels of news that San Francisco is placing cornerback Richard Sherman on short-term injured reserve due to a calf strain, The Athletic reports that cornerback Ahkello Witherspoon is in the concussion protocol. Richard Sherman isn't the only #49ers cornerback injured Sunday. Per a league source, Ahkello Witherspoon suffered a concussion and is