After a week filled with news of nose tackle Aubrayo Franklin contract status, defensive tackle Kentwan Balmer being A.W.O.L., wide receiver Michael Crabtree's neck injury, and the shocker of running back Glen Coffee's abrupt retirement, the 49ers are about to put on the pads and play their first preseason game.

On Sunday, August 15 at 10:00 am, the San Francisco 49ers will play against the Indianapolis Colts. Many questions exist for the 2010 49ers, who many "experts" have predicted would win the NFC West.

After a "so-so" training camp, will quarterback Alex Smith finally be able to live up to his draft pick status? How will that offensive line, now starting two rookies, hold up against a pass rush? Can safety Taylor Mays eventually be the next Ronnie Lott? How will Michael Crabtree look after his first training camp under his belt? Who will step up to take over in place of Coffee?

Some of those questions may be answered on Sunday and fans are eagerly awaiting their team's debut.

San Francisco 49ers at Indianapolis Colts can be watched live at 10:00 am on NFL Network.

Who are you most excited to see play this week?