The San Francisco 49ers are trying to keep pace in the NFC West as they look to improve their record to 8-4. To do that, they'll need a win against the Carolina Panthers at Levi's Stadium on Monday night. Both teams are battling for playoff positioning during the final stretch of the regular season.
San Francisco continues to lean on its high-powered passing attack, while Carolina counters with a strong ground game and a slight edge in time of possession. Both defenses have been inconsistent at times, setting the stage for an intriguing primetime matchup.
The 49ers are coming off a 41-22 victory over the Arizona Cardinals, while the Panthers enter Week 12 after edging out the Atlanta Falcons, 30-27.
| 49ers | Panthers | |
|---|---|---|
| Record | 7-4 (3rd NFCW) | 6-5 (2nd NFCS) |
| Points Per Game | 23.7 (15th) | 18.8 (28th) |
| Total Offense | 349.4 (10th) | 314.3 (22nd) |
| Rushing Offense | 94.8 (27th) | 127.1 (9th) |
| Passing Offense | 254.5 (2nd) | 187.2 (27th) |
| Possession Average | 29:50 (18th) | 31:23 (10th) |
| Points Allowed Per Game | 22.9 (t-14th) | 22.6 (t-12th) |
| Total Defense | 352.9 (25th) | 325.9 (15th) |
| Rushing Defense | 103.8 (12th) | 113.1 (17th) |
| Passing Defense | 249.1 (28th) | 212.8 (16th) |
| Sacks | 12.0 (32nd) | 16.0 (28th) |
| Interceptions | 3 (t-29th) | 7 (t-14th) |
| Punting Avg. (Gross) | 45.0 (28th) | 47.9 (14th) |
| Turnover Differential | -5 (t-25th) | -4 (t-21st) |
49ers by the Numbers
Deommodore Lenoir's Interception Return Impact
Cornerback Deommodore Lenoir has recorded 90 interception return yards this season, the third-most in the NFL (behind LB Devin Lloyd, JAX – 129; and CB Nahshon Wright, CHI – 118).
Kickoff Return Unit Among NFL's Best
The 49ers' kickoff return unit is averaging 28.3 yards per return this season, the fourth-highest mark in the NFL (IND – 29.0; WAS – 28.9; NYJ – 28.5).
Strong Production in Two-Minute Offense
The 49ers offense has scored 26 points in its two-minute offense this season (drives beginning with two minutes or less remaining in a half), the third-most in the NFL (DAL – 33; DEN – 27).
Christian McCaffrey's Touchdown Total
Running back Christian McCaffrey has totaled 11 touchdowns this season (6 rushing, 5 receiving), tied for the second-most in the NFL (RB Jonathan Taylor, IND – 17; RB Josh Jacobs, GB – 11).
49ers Notes
QB Brock Purdy completed 19 of 26 attempts (73.1 pct.) for 200 yards and 3 TDs in Week 11. Surpassed Patrick Mahomes (11 games) and Deshaun Watson (11) for the 2nd-most games with a passer rating of 125-or-higher (min. 15 att. in each game) by a player in his first four seasons in NFL history. Aims for his 6th in a row with 200+ yards and 2+ TDs. Aims for his 3rd in a row with 300+ passing yards at home.
RB Christian McCaffrey had 121 scrimmage yards (81 rush, 40 rec.) and 3 scrimmage TDs (2 rush, 1 rec.) in Week 11. Has 6 rush TDs and 5 rec. TDs this season, becoming the first player in NFL history to record 5+ rush and 5+ rec. TDs in four seasons, surpassing Hall of Famer Marshall Faulk (3 seasons). Became the 5th player since 2000 with 2+ rush TDs and 1+ rec. TD in four career games. Ranks 1st in 2025 with 1,439 scrimmage yards.
WR Jauan Jennings had 4 catches for 54 yards in Week 11. Aims for his 6th in a row with 4+ catches. Aims for his 5th in a row with 40+ rec. yards. Has a rec. TD in 2 of his past 3 games.
TE George Kittle had 6 catches for 67 yards and 2 TDs in Week 11. Became the 5th TE in NFL history with 7,500+ rec. yards and 50 rec. TDs in a player's first 9 seasons. Aims for his 5th in a row with 4+ catches. Has a rec. TD in 3 of his past 4 games.
LB Curtis Robinson led the team and had a career-high 11 tackles in Week 11. Has 5+ tackles in 2 of his past 3 road games.
LB Dee Winters had 10 tackles and a TFL in Week 11. Aims for his 5th in a row with 5+ tackles. Aims for his 3rd in a row with a TFL.
DB Deommodore Lenoir had 7 tackles, 2 PDs, and INT return yards in Week 11. Had 8 tackles in the last meeting.
S Ji'Ayir Brown had 7 tackles in Week 11. Has 5+ tackles in 4 of his past 5 games. Has a PD in 2 of his past 3 games.
Panthers Notes
The Panthers last week became the first team since San Francisco in Week 10 of the 2024 season to have five players with 50+ receiving yards in the same game.
QB Bryce Young passed for a franchise-record 448 yards, 3 TDs, and a 123.2 passer rating in Week 11. Became the 5th QB under age 25 with 30+ completions, 425+ pass yards, 3+ TD passes, and 0 INTs in a single game in NFL history. Has a pass TD in 9 of his past 10 road games.
RB Rico Dowdle had 100 scrimmage yards (55 rec., 45 rush) in Week 11. Ranks 4th with 833 rush yards in 2025. Is one of four NFC RBs with an active streak of 50 scrimmage yards in 7+ consecutive games. Has a rush TD in 2 of his past 3 games.
WR Tetairoa McMillan had 8 catches for 130 yards and 2 TDs in Week 11, becoming the 6th rookie since 2000 with 8+ catches, 130+ yards, and 2 TDs in a game. Joined Ja'Marr Chase, Malik Nabers, Puka Nacua, and Chris Olave as the only rookies in the last five seasons to record 50+ catches and 700+ yards in their first 11 games. Ranks 1st among rookies and 5th in the NFC with 748 receiving yards.
WR Xavier Legette had 4 catches for 83 yards and a TD in Week 11. Has 80+ yards and a TD in 2 of his past 3 road games.
LB Christian Rozeboom had 10 tackles and a TFL last week. Aims for his 3rd in a row with 10+ tackles and a TFL on the road. Has 10+ tackles and a TFL in 3 of his past 4 games.
CB Mike Jackson had 2 tackles and a PD in Week 11. Tied for 4th in 2025 with 11 PD. Has a PD in 4 of his past 5 games.
CB Corey Thornton had 5 tackles, 2 PD, and a FF in Week 11 and is one of three NFC DBs to record 5+ tackles, 2 PD, and a FF in a single game this season.
S Tre'Von Moehrig had a team-high 11 tackles in Week 11 and is one of three DBs with two games of 11+ tackles in 2025. Has 5+ tackles in 7 of his past 8 road games. Has a TFL in 2 of his past 3 road games.