The San Francisco 49ers are facing the Tampa Bay Buccaneers at Raymond James Stadium in Week 6. Below are the latest in-game injury updates for the 49ers. This article will be updated in real time as new information becomes available.
Players are listed in order of most recent report.
LB Fred Warner (ankle, out)
Fred Warner went down in the first quarter and was quickly attended to by medical staff, who examined his right leg before carting the star linebacker off the field. He was fitted with an air cast as he was taken to the locker room.
Warner's right leg was in an air cast as he was carted off 🙏
(via @NFLonCBS) https://t.co/vB7Horkowx pic.twitter.com/Iyum25hRft
— 49ers on NBCS (@NBCS49ers) October 12, 2025
The 49ers quickly ruled Warner out with an ankle injury, which looked serious based on the replay.
Update: The Athletic's Dianna Russini reports that Warner suffered a dislocated right ankle. He will meet with doctors to assess the injury's severity and determine how much time he will miss.
NEWS: 49ers LB Fred Warner suffered a dislocated right ankle Sunday vs. the Buccaneers, per source.
San Francisco's All-Pro linebacker will meet with doctors to determine how much time he will miss. pic.twitter.com/KQoWfyITLk
— Dianna Russini (@DMRussini) October 12, 2025