The San Francisco 49ers are preparing for their Week 3 contest against the Arizona Cardinals on Sunday at Levi's Stadium in Santa Clara, California.
The most significant development from Wednesday's injury report is Brock Purdy's return to practice—though only as a limited participant. The quarterback is working his way back from the toe injury he suffered in Week 1 against the Seattle Seahawks. In his absence, Mac Jones started Week 2 against the New Orleans Saints.
When asked if Purdy has a chance to play this weekend against the Arizona Cardinals, head coach Kyle Shanahan responded, "Yeah, he does have a chance."
Players who were injured against the Saints and did not practice on Wednesday are offensive lineman Spencer Burford (knee), wide receiver Jauan Jennings (ankle, shoulder), fullback Kyle Juszczyk (concussion), and cornerback Siran Neal (concussion).
Tackle Trent Williams (knee), who was a true game-time decision against the Saints, also did not practice. However, he often receives veteran rest days during the first practice of the week. Williams' participation in Thursday's session will provide a clearer indication of his availability for Week 3.
Below are Wednesday's practice participation reports for both the 49ers and Cardinals, which were provided by the 49ers Communications staff.
San Francisco 49ers Wednesday Practice
Did Not Participate In Practice
DE Nick Bosa (not injury related - resting player), T Spencer Burford (knee), DE Yetur Gross-Matos (knee), WR Jauan Jennings (ankle, shoulder), FB Kyle Juszczyk (concussion), RB Christian McCaffrey (calf, resting player), S Siran Neal (concussion), T Trent Williams (knee, resting player)
Limited Participation in Practice
QB Brock Purdy (left shoulder, toe)
Full Participation in Practice
RB Jordan James (finger)
Arizona Cardinals Wednesday Practice
Did Not Participate In Practice
CB Will Johnson (groin)
Limited Participation in Practice
T Kelvin Beachum (not injury related - resting player), G Will Hernandez (knee), T Paris Johnson (knee), CB Max Melton (knee), TE Tip Reiman (foot), LB Cody Simon (concussion), DE Dante Stills (elbow)