The San Francisco 49ers are preparing for their Week 1 contest against the Seattle Seahawks on Sunday at Lumen Field in Seattle, Washington. Both teams have released their official injury reports, which are provided below.
San Francisco 49ers
Doubtful
RB Jordan James (finger), WR Jordan Watkins (ankle)
Questionable
RB Christian McCaffrey (calf)
Seattle Seahawks
Out
WR Jake Bobo (concussion), LB Uchenna Nwosu (knee), WR Dareke Young (hamstring)
Injury Notes
Running back Christian McCaffrey (calf) suited up for practice and was spotted doing individual work on the side while his teammates went through warmups and the early portion of individual drills. Reporters are only allowed to observe the opening portion of practice and must leave before team drills begin.
The 49ers listed McCaffrey as a "limited participant" on Thursday. He is officially listed as "questionable" for Sunday's game.
Head coach Kyle Shanahan clarified that McCaffrey did not participate in full-team practice on Friday, though reporters noted he was active on the side early in the session.
Christian McCaffrey is suited up on side as warmup start , a day after he was limited by a calf issue. Not sure he'll actually practice with team in walk-through. He typically warms up on own. pic.twitter.com/6qc95rRb4E
— Cam Inman (@CamInman) September 5, 2025
Shanahan refrained from providing any further details surrounding McCaffrey's status, adding, "I'm not going to say anything about Christian, guys, or any of our players' injuries."
When asked about his level of concern regarding McCaffrey's availability, Shanahan simply replied, "It's questionable. Questionable concern."
Below are Friday's practice participation reports for both the 49ers and Seahawks, which were provided by the 49ers Communications staff.
San Francisco 49ers Friday Practice
Did Not Participate In Practice
DE Yetur Gross-Matos (knee), RB Christian McCaffrey (calf)
Limited Participation in Practice
RB Jordan James (finger), WR Jordan Watkins (ankle)
Full Participation in Practice
G Ben Bartch (elbow), DT Kalia Davis (groin), RB Isaac Guerendo (shoulder), DE Bryce Huff (ankle), WR Jauan Jennings (calf), QB Mac Jones (knee), DE Sam Okuayinonu (shoulder), S Jason Pinnock (heel), G Dominick Puni (knee), CB Upton Stout (calf), DT C.J. West (knee), DE Mykel Williams (knee), T Trent Williams (not injury related - resting player)
Seattle Seahawks Friday Practice
Did Not Participate In Practice
WR Dareke Young (hamstring)
Limited Participation in Practice
WR Jake Bobo (concussion), LB Uchenna Nwosu (knee)
Full Participation in Practice
G Anthony Bradford (back), WR Tory Horton (ankle), WR Cody White (shoulder), CB Tariq Woolen (illness)