The San Francisco 49ers have officially released their 2025 jersey schedule, revealing which uniforms they'll wear each week of the regular season. This year, the team is making a noticeable change early on—opting for white uniforms in their first two home games at Levi's Stadium to help beat the September heat in Santa Clara.
The 49ers will wear their white throwback alternates when they host the Arizona Cardinals on September 21 in their home opener. The following weekend, September 28, San Francisco will wear their primary white jerseys against the Jacksonville Jaguars.
For the first time, the 49ers will wear their white jerseys for early-season home games to combat the possible heat factor at Levi's Stadium. They will wear white throwbacks in Week 3 vs. the Cardinals and their primary white uniforms in Week 4 vs. the Jaguars.
— Matt Maiocco (@MaioccoNBCS) August 31, 2025
That strategy means the 49ers will wear their iconic red primary jerseys just three times this season, compared to 10 games in their white primary jerseys. Fans can also expect a mix of throwback looks and the black "Rivalries" uniform late in the year.
Full 2025 49ers jersey schedule
Red primary
Week 10: Rams
Week 12: Panthers
Week 15: Titans
White primary
Week 1: at Seahawks
Week 2: at Saints
Week 4: Jaguars
Week 5: at Rams
Week 6: at Buccaneers
Week 8: at Texans
Week 9: at Giants
Week 11: at Cardinals
Week 13: at Browns
Week 16: at Colts
Red throwback
Week 7: Falcons
Week 17: Bears
White throwback
Week 3: Cardinals
Black Rivalries
Week 18: Seahawks
Getting the fits lined up 👏 pic.twitter.com/KnRR1kOv2h
— San Francisco 49ers (@49ers) August 31, 2025
With the mix of throwbacks, primaries, and the black alternate, this year's 49ers uniform schedule offers a variety of options for fans heading to Levi's Stadium or watching from home.