The San Francisco 49ers return home to face the Kansas City Chiefs at Levi's Stadium in their 15th all-time meeting. San Francisco aims to improve to 6-2 at home against Kansas City.
Previous game
The 49ers are coming off a 36-24 road victory over the Seattle Seahawks. Quarterback Brock Purdy led the offense, completing 18 of his 28 passing attempts for 255 yards and three touchdowns, achieving a passer rating of 129.3. Wide receiver Deebo Samuel Sr. registered a team-high 102 yards on three receptions, highlighted by a 76-yard touchdown catch. Tight end George Kittle added five receptions for 58 yards and two touchdowns, while fullback Kyle Juszczyk contributed a six-yard touchdown on his only carry.
On defense, the 49ers held the Seahawks to just 52 rushing yards. Linebacker Fred Warner led the unit with 11 tackles, a pass defensed, and a forced fumble. Cornerback Renardo Green and safety Malik Mustapha each recorded their first career interceptions, picking off Seahawks quarterback Geno Smith. Defensive lineman Sam Okuayinonu also made an impact, notching two tackles and a sack.
Below is everything you need to know to follow the upcoming game.
When does the game start?
Sunday, October 20 at 1:25 p.m. PT
Where is the game being played?
Levi's Stadium in Santa Clara, California
Who are the head coaches?
49ers: Kyle Shanahan
Chiefs: Andy Reid
Betting Odds
As of October 16, the 49ers are favored by 1.5 points in this game, with an over/under set at 47 points.
What channel is the game on?
Network: FOX
Play-By-Play: Kevin Burkhardt
Color Analyst: Tom Brady
Sideline Reporter: Erin Andrews
Sideline Reporter: Tom Rinaldi
Viewers outside the broadcast area can watch the game via NFL Sunday Ticket on YouTube TV or YouTube Premium, but a subscription to the package is required.
What areas will receive the broadcast?
According to 506sports.com, this game will be broadcast nationally on FOX in all markets that are scheduled to receive a late game on the network.
Where can I stream the game?
NFL Sunday Ticket subscribers can stream the game using the YouTube TV app. Those who purchased through YouTube Premium can watch via the YouTube app. Additionally, NFL+ subscribers can stream the game in its entirety once the matchup has been completed.
Bay Area fans can stream the game through the official 49ers app or at 49ers.com.
Where can I listen to the radio broadcast?
49ers Radio
Bay Area fans can listen on KGO 810 AM and The Bone 107.7 FM, where Greg Papa and Tim Ryan will call the game.
Jesús Zárate and Carlos Yustis will call the game in Spanish. That broadcast can be heard at 49ers.com/news/Espanol.
Chiefs Radio
Kansas City area fans can listen on The Fan 96.5 FM, where Mitch Holthus and Danan Hughes will call the game.
National Radio
Fans can listen via Compass Media Networks, where Chris Carrino and Brian Baldinger will call the game.
Streaming
NFL+ subscribers can listen to the game through that service.
Game discussion
Fans can discuss the game within our Niner Talk forum.
How has this series played out historically?
Matchups: 14
Series Record: Series is tied 7-7
49ers Home Record vs. Chiefs: 49ers lead series 5-2
49ers Away Record vs. Chiefs: Chiefs lead series 5-2
First Meeting: 12/6/71, Chiefs win 26-17, at SF
Last Meeting: 10/23/22, Chiefs win 44-23, at SF
Current Streak: Lost 4
Longest 49ers Win Streak: 4 (10/5/75 – 12/14/91)
Longest Chiefs Win Streak: 4 (9/23/18 – 2/11/24)
Most 49ers Points: 31 (11/17/85): 49ers win 31-3, at SF
Most Chiefs Points: 44 - 2 times (Last: Chiefs win 44-23, at SF
49ers Shutouts: None
Chiefs Shutouts: 1 (10/1/06): Chiefs win 41-0, at KC
49ers Notes
- QB Brock Purdy passed for 255 yards and 3 touchdowns with no interceptions, earning a 129.3 rating in Week 6. It marked his eighth regular-season game with 3+ touchdown passes and 0 interceptions, tying him for the third-most by a quarterback within their first three NFL seasons. He also has 12 games with a passer rating of 120+, tying Russell Wilson for the most by a quarterback in their first three seasons all-time. Purdy has 24 total touchdowns (22 passing, 2 rushing) and a 109 rating in 13 regular-season home starts. He threw for 255 yards and a touchdown against Kansas City in Super Bowl LVIII.
- RB Jordan Mason had 82 scrimmage yards (73 rushing, 9 receiving) in Week 6 and is aiming for his seventh consecutive game with 80+ scrimmage yards.
- RB Isaac Guerendo (rookie) rushed for a career-high 99 yards last week.
- FB Kyle Juszczyk scored his first rushing touchdown of the season in Week 6. He has 3 receiving touchdowns in 5 career games against Kansas City, including postseason matchups.
- TE George Kittle had 5 receptions for 58 yards and 2 touchdowns last week, marking his seventh career regular-season game with multiple touchdown catches. He is looking for his third straight home game and fifth consecutive game overall with a touchdown reception. He recorded 6 catches for 98 yards and a touchdown in his last home matchup against Kansas City.
- WR Deebo Samuel posted 117 scrimmage yards (102 receiving, 15 rushing) and caught his first touchdown pass of the season last week. It was his 15th career game with 100+ receiving yards, and he became the first wide receiver in NFL history with 20+ receiving touchdowns and 20+ rushing touchdowns. Samuel has tallied 70+ scrimmage yards in 4 of his 5 games this season.
- WR Jauan Jennings recorded a touchdown reception and a touchdown pass in Super Bowl LVIII against Kansas City, becoming only the second player (after Nick Foles) to achieve both a receiving and passing touchdown in a Super Bowl.
- WR Brandon Aiyuk had 7 receptions for 82 yards in his last home game against Kansas City.
- LB Fred Warner registered 11 tackles and tied his career high with his fourth forced fumble of the season last week. He is only the second player since 2000 (after Marlon Humphrey in 2020) to record 4 forced fumbles and 5 passes defensed within his team's first 6 games of a season. Warner recorded 13 tackles in Super Bowl LVIII against Kansas City and aims for his fifth consecutive game against the Chiefs, including postseason, with 6+ tackles.
- DL Nick Bosa is looking for his third consecutive home game with a tackle for loss. He has 2 sacks and 3 tackles for loss in 3 career games against Kansas City, including postseason play.
- Rookies S Malik Mustapha and CB Renardo Green each recorded their first career interceptions last week.
Chiefs Notes
- The Chiefs are seeking their third 6-0 start in franchise history (2003 and 2013) and can become the 10th defending Super Bowl champion to begin a season 6-0. They have won their first game following a bye week in 5 of the past 6 seasons.
- QB Patrick Mahomes set season highs in completions (28) and passing yards (331) in Week 5, marking his 46th career game with 300+ passing yards—the most ever by a player in their first 8 seasons. Mahomes is 4-0 against San Francisco, including playoffs, with 1,356 passing yards (339 per game), 11 total touchdowns (10 passing, 1 rushing), and a 104.6 rating. He has recorded 2+ touchdown passes in each game and 300+ passing yards in 3 of those 4 starts.
- RB Kareem Hunt had 117 scrimmage yards (102 rushing, 15 receiving) and a rushing touchdown in Week 5, his first 100-yard game since September 26, 2021 (with Cleveland). He aims for his third straight game with 85+ scrimmage yards and has 3 rushing touchdowns in 2 career games against San Francisco.
- TE Travis Kelce is looking for his third consecutive game with 7+ catches and 70+ receiving yards. He recorded 9 catches for 93 yards in Super Bowl LVIII against San Francisco and is aiming for his fifth straight game against the team with 6+ catches, including playoffs.
- WR JuJu Smith-Schuster had 7 receptions for a team-high 130 yards in Week 5. He has 10 catches for 205 yards (102.5 per game) and 2 touchdowns in 2 career games against San Francisco.
- WR Xavier Worthy scored a rushing touchdown in Week 5 and is the only rookie with multiple rushing touchdowns (2) and receiving touchdowns (2) this season.
- WR Mecole Hardman had the game-winning touchdown catch in overtime against San Francisco in Super Bowl LVIII and is looking for his third consecutive game against them with a receiving touchdown.
- DT Chris Jones has a sack in 2 of his last 3 road games. He recorded 2 sacks and a forced fumble in his last regular-season meeting with San Francisco.
- LB Nick Bolton led the team with a season-high 11 tackles and had 2 tackles for loss in Week 5. He made 13 tackles in Super Bowl LVIII against San Francisco and is aiming for his third straight game against them with 10+ tackles.
- S Bryan Cook had 2 passes defensed and his first interception of the season in Week 5. He has recorded a pass defensed in 3 of the last 4 games.