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The San Francisco 49ers improved to 5-4 on the season after a 22-16 Week 10 win against to the Los Angeles Chargers at Levi's Stadium in Santa Clara, California.
Below are several statistics and notes from Sunday's game, which were provided by the 49ers Communications staff.
With the Win…
- The 49ers improved to 8-8 overall against the Chargers, including a 4-3 mark at home.
- The Niners defeated the Chargers for the first time since 2000 [W, 45-17 at SD (12/3/00)].
- San Francisco has won back-to-back games for the first time this season.
- The 49ers are now 3-1 at home in 2022.
- Head coach Kyle Shanahan improves to 1-1 against the Chargers as the head coach of the 49ers.
Offense
- The 49ers offense finished with 41 rushing atts. for 157 yds. and 2 TDs on the night. San Francisco improved to 8-0 in the regular season, and 2-0 in 2022, when registering 40-or-more rushing atts. in a single game under head coach Kyle Shanahan.
49ERS GAMES WITH 40-OR-MORE RUSHING ATTS., 2017-22
| Date | Opp. | Rush Atts. | Rush Yds. | Result |
| 9/15/19 | at Cin. | 42 | 259 | W, 41-17 |
| 9/22/19 | vs. Pit. | 40 | 168 | W, 24-20 |
| 10/7/19 | vs. Cle. | 40 | 275 | W, 31-3 |
| 10/13/19 | at LAR | 41 | 99 | W, 20-7 |
| 11/15/21 | vs. LAR | 44 | 156 | W, 31-10 |
| 11/21/21 | at Jax. | 42 | 171 | W, 30-10 |
| 9/18/22 | vs. Sea. | 45 | 189 | W, 27-7 |
| 11/13/22 | vs. LAC | 41 | 157 | W, 22-16 |
Jimmy Garoppolo
- QB Jimmy Garoppolo completed 19 of 28 atts. for 240 yds. to go along with 5 carries for 3 yds. and 1 TD.
- The rushing TD marked Garoppolo's 2nd of the season and 7th of his career.
Christian McCaffrey
- RB Christian McCaffrey registered 14 carries for 38 yds. and 1 TD to go along with 4 recepts. for 39 yds.
- McCaffrey has registered 1-or-more rushing TDs in back-to-back games for the 12th time in his career and the first time since Weeks 1-2 of the 2020 season.
Deebo Samuel
- WR Deebo Samuel tallied 2 recepts. for 24 yds. to go along with 4 carries for 27 yds.
- With 2 recepts., Samuel has now registered 201 career recepts. In just 46 career games, he has registered 200 career recepts. in the 3rd-fewest amount of games by a member of the 49ers dating back to 1970 [TE George Kittle – 43 games & WR Jerry Rice – 44 games].
FASTEST MEMBER OF THE 49ERS TO 200 RECEPTS., SINCE 1970
| Player | Games |
| TE George Kittle | 43 |
| WR Jerry Rice | 44 |
| WR Deebo Samuel | 46 |
| WR Michael Crabtree | 48 |
| WR Dwight Clark | 50 |
- With 24 yds., Samuel has now registered 3,009 career rec. yds. In just 46 career games, he has registered 3,000 career rec. yds. in the 3rd-fewest amount of games by a member of the 49ers dating back to 1970 [WR Jerry Rice – 38 games & WR Vic Washington – 44 games].
FASTEST MEMBER OF THE 49ERS TO 3,000 REC. YDS., SINCE 1970
| Player | Games |
| WR Jerry Rice | 38 |
| WR Vic Washington | 44 |
| WR Deebo Samuel | 46 |
| TE George Kittle | 47 |
| WR Dwight Clark | 55 |
| WR Michael Crabtree | 55 |
Talanoa Hufanga
- S Talanoa Hufanga finished with 2 tackles and registered 1 INT of Chargers QB Justin Herbert. He now has 4 INTs on the season and his career.
- Hufanga's 4 INTs this season are the most by a member of the 49ers in a single season since CB Perrish Cox registered 5 INTs in 2014.
Nick Bosa
- DL Nick Bosa brought down Herbert for a 1-yd. sack, giving him 9.5 on the season and 34.0 in his career.
- Bosa has now registered 1.0-or-more sacks in 7 of his 8 games played this season.
Charles Omenihu
- DL Charles Omenihu brought down Herbert for a 7-yd. sack and a FF. The sack marked his 4th of the season and 11th of his career and the FF marked the 3rd of his career and first since 2019 as a member of the Houston Texans [at KC (10/23/19)].
- It also marked Omenihu's 3rd career game with 1.0-or-more sacks and 1-or-more FFs.
Jordan Willis
- DL Jordan Willis registered 4 tackles and 1.0 sack of Chargers QB Chase Daniel. The sack was Willis' first of the season and gave him 9.5 in his career.
