49ers-Rams Injury Report: Jimmy Garoppolo limited; Trent Williams, Elijah Mitchell don’t practice

The San Francisco 49ers are preparing for their Week 18 contest against the Los Angeles Rams on Sunday at SoFi Stadium in Inglewood, California.

Jimmy Garoppolo returned to practice for the first time since suffering his thumb injury against the Tennessee Titans on December 23. Although, the quarterback was limited.

"We'll put Jimmy in on what he feels comfortable doing with where he's at today," Shanahan said. "Trey will get the rest. I'm sure Trey will get the majority, but we'll see how it is when [they are] out there. Mainly just communicating with them throughout the practice, through the individuals, through everything. Today won't be a full-speed practice, so it's not as challenging."

Garoppolo admitted that throwing the football is painful. He had an opportunity to throw on Tuesday to feel what it is like.

"F--k, it hurts," Garoppolo told reporters. "I don't know how else to describe it. It feels like the web in your hand is kind of tearing a little bit. That's probably the best way I can describe it."

While Trent Williams did not practice, Shanahan is optimistic the offensive tackle will play on Sunday.

"I know [his elbow is] hurting too much to go today," Shanahan said. "... I know this is a big game and if Trent can be out there, he'll be out there. I don't think he's looking at it in any other way right now."

Shanahan also didn't sound too concerned about the 49ers' leading rusher, rookie running back Elijah Mitchell.

"He still has the same stuff he's had the last few weeks," Shanahan said, "so that's why he's not going today. I think we're listing knee as the injury."

Below are Wednesday's practice participation reports for both the 49ers and Rams, which were provided by the 49ers Communications staff.

San Francisco 49ers Wednesday Practice

Did Not Participate In Practice
LB Azeez Al-Shaair (knee), DE Nick Bosa (not injury related - resting player), C Alex Mack (not injury related - resting player), RB Elijah Mitchell (knee), T Trent Williams (elbow)

Limited Participation in Practice
QB Jimmy Garoppolo (right thumb), LB Dre Greenlaw (groin), S Talanoa Hufanga (knee), DT Maurice Hurst (calf), S Jaquiski Tartt (shoulder)

Los Angeles Rams Wednesday Practice

Did Not Participate In Practice
DT Aaron Donald (not injury related - resting player), LB Leonard Floyd (not injury related - resting player), CB Jalen Ramsey (not injury related - resting player), DT A'Shawn Robinson (not injury related - resting player), T Andrew Whitworth (not injury related - resting player)

Limited Participation in Practice
S Nick Scott (thumb)

Full Participation in Practice
RB Cam Akers (Achilles)