49ers at Titans, Week 16 predictions: Fan-favored Niners look to win 3 in a row

The Tennessee Titans are set to host the San Francisco 49ers at Nissan Stadium in Nashville, Tennessee on Thursday, December 23 at 5:20 p.m. PT. Each week, the 49ers Webzone staff predicts the winner within its annual NFL Pick 'em contest. That includes writers and forum moderators.

All 10 participating staff members this week selected the 49ers to beat the Titans. San Francisco is currently a three-point favorite. If the Niners win, it will be their third straight victory and sixth in the past seven games.

As for all the fans who are taking part in our NFL Pick 'em contest, 83 percent have the 49ers winning the game, as of this post.

Of all the Week 16 game predictions, the most lopsided result comes from Sunday's matchup between the New York Giants and the Philadelphia Eagles. Voting has 98 percent of fans believing the Eagles will earn the victory.

When it comes to the predictions, the closest matchup is between the Buffalo Bills and the New England Patriots on Sunday, with 57 percent selecting the Bills to win the game.

Below is a breakdown of all 16 matchups for the upcoming slate of NFL games.