We've known since the end of last season which opponents the San Francisco 49ers will face in 2019. What isn't known are the dates and times for each matchup. That will change when the NFL officially announces the complete 2019 schedule on Wednesday, April 17 at 5 p.m. PT (8 p.m. ET).
As we just noted on @GMFB , the 2019 NFL regular-season schedule will be released at 8 pm ET tomorrow on @nflnetwork.
NFL Network will debut the complete schedules for all 32 teams during a schedule release show at that time.
The 49ers will meet each NFC West team twice, as they do each year. San Francisco will also face each team within the AFC North and NFC South once and last season's third-place opponents from the NFC North and NFC East.
The schedule will also include four trips (Baltimore, Cincinnati, Tampa Bay, Washington) to the Eastern time zone, where San Francisco has not won a game since the 2014 season (at New York Giants on November 16, 2014).
Below are the opponents the 49ers are slated to play during the upcoming season.
Home Opponents
Arizona Cardinals
Los Angeles Rams
Seattle Seahawks
Atlanta Falcons
Carolina Panthers
Cleveland Browns
Green Bay Packers
Pittsburgh Steelers
Road Opponents
Arizona Cardinals
Los Angeles Rams
Seattle Seahawks
Baltimore Ravens
Cincinnati Bengals
New Orleans Saints
Tampa Bay Buccaneers
Washington Redskins
Why the 49ers' 2025 Schedule Could Be Their Golden Ticket Back to the NFC West Throne
By Carlos Torres
13 hrs
Tomorrow, May 14th, 2025, at 8 p.m. ET, the NFL world will turn its attention to the unveiling of the 2025 schedule. This release carries significant weight for the San Francisco 49ers and their faithful, potentially outlining the path back to NFC West supremacy.
Based on...
49ers offensive coordinator says Mac Jones capable of being NFL starter
By Marc Adams
May 10
Klay Kubiak isn't just coaching Mac Jones—he's betting on him. As the San Francisco 49ers opened rookie minicamp on Thursday, the new offensive coordinator didn't hesitate to voice his belief in the former first-round pick. Speaking to reporters, Kubiak praised Jones'...
Breer reveals Panthers were 49ers' trade-up target in NFL Draft
By David Bonilla
May 5
The first 10 picks of the 2025 NFL Draft were tense for San Francisco 49ers general manager John Lynch and head coach Kyle Shanahan. As they watched the board unfold, they hoped one name wouldn't be called—Georgia defensive end Mykel Williams, the top player on their...
John Lynch: 49ers received 8 to 10 trade calls in Round 1 of NFL Draft
By David Bonilla
May 6
There's always a flurry of communication between NFL teams during the draft, as front offices gauge opportunities to move up or down the board. For the San Francisco 49ers, the opening night of the 2025 NFL Draft was no exception. General manager John Lynch recently joined the...