Following the play, Hyde left for the 49ers locker room to be evaluated. He was walking under his own power, but with a slight limp. Hyde entered the game needing 50 yards to hit the milestone, which he is unlikely to achieve this week.
Hyde was ruled out for the remainder of the game.
Update:
Following the game, Hyde said that he would have an MRI on his knee on Sunday but remained hopeful that he could play next week against the Seattle Seahawks.