Earlier this season, the Giants beat the Patriots 24-20.
Kickoff is scheduled for 3:30 PM on NBC at Lucas Oil Stadium in Indianapolis, Indiana. You can also watch the game online at NBC Sports. You can also follow the statistics live on NFL.com's Game Center.
In the final week of our NFL Pick 'Em contest, 55% of fans believe that the Giants will win Super Bowl XLVI. Within Sportstacular, a popular mobile scores app, fans are 50/50 on who will win tonight.
Visit our NFL Talk forum to discuss the game.
More San Francisco 49ers News
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49ers expected to target Super Bowl-winning cornerback in free agency
Speculation surrounding the San Francisco 49ers' secondary intensified at the NFL Scouting Combine after Dan Graziano and Ben Solak of ESPN reported that the team could explore a trade involving starting cornerback Renardo Green. Graziano estimated there is an 80% chance the... -
49ers' Trent Williams reveals emotional toll of Super Bowl loss
San Francisco 49ers left tackle Trent Williams still feels the sting of falling short on the NFL's biggest stage. When the Kansas City Chiefs scored the game-winning touchdown in Super Bowl LVIII, Williams said he struggled to process that it was over. For years, he dreamed of... -
49ers linked to veteran WR with off-field concerns
The San Francisco 49ers are widely expected to address the wide receiver position this offseason as they reshape the roster for 2026. Brandon Aiyuk appears headed out after a rift with the organization, while Jauan Jennings, Kendrick Bourne, and Skyy Moore are all scheduled to... -
49ers can cross star tight end off free agency list after new report
If the San Francisco 49ers had an interest in adding a marquee tight end this offseason, they can scratch one big name off the list. According to NFL insider Ian Rapoport, the Atlanta Falcons plan to place the franchise tag on tight end Kyle Pitts, fully guaranteeing him more...