Inactives:
- RB Israel Abanikanda
- G Aaron Banks (concussion)
- DE Nick Bosa (hip, oblique)
- QB Joshua Dobbs
- LB Demetrius Flannigan-Fowles (knee)
- T Trent Williams (ankle)
- CB Rock Ya-Sin
Several players were officially ruled out on Friday, including left tackle Trent Williams, who will miss his third consecutive game due to an ankle injury.
Linebacker Dre Greenlaw remains on the physically unable to perform (PUP) list as he works his way back from a torn Achilles. There is optimism he could be activated ahead of Thursday's game against the Los Angeles Rams.
On Saturday, the 49ers placed two players on injured reserve: running back Jordan Mason and safety George Odum. Mason suffered a high-ankle sprain during last week's game against the Buffalo Bills, while Odum sustained a knee injury during practice last week.
Additionally, the 49ers downgraded two key players to "out" on Saturday. Defensive end Nick Bosa, initially listed as doubtful, will miss his third straight game as he deals with hip and oblique injuries. Left guard Aaron Banks, who remains in the concussion protocol, was initially questionable but has also been ruled out.
In response to these roster challenges, the 49ers made several adjustments on Saturday. Offensive lineman Sebastian Gutierrez was promoted from the practice squad to the active roster. Linebacker Jalen Graham and running back Ke'Shawn Vaughn were elevated from the practice squad.
Recently acquired running back Israel Abanikanda will not be active for the game. The 49ers' available running backs will be Isaac Guerendo, Patrick Taylor, and Ke'Shawn Vaughn. Additionally, linebacker Demetrius Flannigan-Fowles, who was questionable with a knee injury, has also been ruled inactive.
In a positive development, safety Talanoa Hufanga was activated from injured reserve. He is set to return to action after recovering from a wrist injury.
Related News
More San Francisco 49ers News
-
Several 49ers land in Prisco's Top 100 NFL Players of 2026 list
Longtime CBS Sports scribe Pete Prisco released his Top 100 NFL Players of 2026 list, which he shares annually. Six San Francisco 49ers earned spots on the ranking. Leading the way for the 49ers is star linebacker Fred Warner, who continues to be regarded as one of the NFL's... -
Brandon Aiyuk takes another shot at 49ers, calling John Lynch "creepy," Kyle Shanahan "a toddler"
Brandon Aiyuk added more fuel to the fire Saturday morning, sharing a video that gives his perspective on his ongoing situation with the San Francisco 49ers, including his relationship with his agent, his frustrations with the organization, and his thoughts on general manager... -
'We get to hit people in the face': 49ers' George Kittle sends fiery message to division rivals
San Francisco 49ers fans were understandably frustrated watching the Seattle Seahawks capture Super Bowl LX at Levi's Stadium in Santa Clara. Seeing a division rival celebrate a championship on your home field is never easy. 49ers All-Pro linebacker Fred Warner understands... -
49ers fans take note: NFL insider warns 'the 18-game slate is coming'
San Francisco 49ers fans would undoubtedly welcome another opportunity each season to watch their favorite team take the field. According to one NFL insider, that extra game is likely on the horizon—it's simply a matter of when the league and players can agree on the...