Below are the official injury status reports for the two teams.
San Francisco 49ers
Questionable
LB Oren Burks (shoulder), DT Kalia Davis (ankle)
Detroit Lions
Out
G Jonah Jackson (knee), WR Kalif Raymond (knee)
Questionable
QB Hendon Hooker (tooth), CB Chase Lucas (illness)
Notes
Head coach Kyle Shanahan shared good news after Friday's practice. Deebo Samuel is full-go for Sunday's game. The wide receiver has practiced two consecutive days after sitting out Wednesday's session, and there was growing confidence inside the building that he would be healthy enough to play against the Lions.
"It's kind of out of sight, out of mind right now," Shanahan said, noting that the pain in Samuel's shoulder has subsided throughout the week.
Speaking to reporters after Friday's practice, Samuel was asked if he might need to protect his shoulder on Sunday. He responded, "I ain't protecting nothing."
RELATED: Deebo Samuel practices for second consecutive day
The 49ers are in relatively good health as they compete to advance to Super Bowl 58 in Las Vegas. Only two players, linebacker Oren Burks and defensive tackle Kalia Davis, are listed as "questionable."
Lions tight end Sam LaPorta, who has been dealing with a knee injury, was a full practice participant on Friday and has been cleared to play against the 49ers.
Below are Friday's practice participation reports for both the 49ers and Lions, which were provided by the 49ers Communications staff.
San Francisco 49ers Friday Practice
Limited Participation in Practice
LB Oren Burks (shoulder)
Full Participation in Practice
DT Arik Armstead (foot, knee), DT Kalia Davis (ankle), LB Dre Greenlaw (Achilles), S George Odum (biceps), WR Deebo Samuel (shoulder), CB Ambry Thomas (hand)
Detroit Lions Friday Practice
Did Not Participate In Practice
QB Hendon Hooker (tooth), G Jonah Jackson (knee), WR Kalif Raymond (knee)
Limited Participation in Practice
CB Chase Lucas (illness)
Full Participation in Practice
LB Alex Anzalone (shoulder, ribs), LB James Houston (ankle), TE Sam LaPorta (knee), C Frank Ragnow (ankle, toe, knee, back), WR Josh Reynolds (ribs)