To clinch the top seed, the 49ers must also see the Detroit Lions and Philadelphia Eagles lose their Week 17 matchups. The Lions are set to face the Dallas Cowboys on the road, while the Eagles will host the Arizona Cardinals. Dallas is currently a six-point favorite, and Philadelphia is a 10.5-point favorite in their respective games.
The 49ers are heavy 13.5-point favorites over the Commanders. Following their journey to the East Coast, Kyle Shanahan's squad will return home to conclude the regular season against the Los Angeles Rams.
Below is the current playoff seed order in the NFC, with division leaders highlighted.
- San Francisco 49ers (11-4)*
- Detroit Lions (11-4)*
- Philadelphia Eagles (11-4)*
- Tampa Bay Buccaneers (8-7)
- Dallas Cowboys (10-5)*
- Los Angeles Rams (8-7)
- Seattle Seahawks (8-7)
* Clinched playoff spot
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