Of course, this isn't a new update. On Friday, head coach Kyle Shanahan informed everyone that Gregory would not play. The defender was in Santa Clara for his physical on Friday but was headed back to Denver. He will reunite with his new teammates on Monday.
"He came in today, took his physical and stuff, so just got a chance to meet him," Shanahan told reporters. "... But he's going to head back today, see his family, get his stuff, and he'll be out here Monday."
The 49ers coach joked about Gregory's availability for the game.
"I don't want to give our secrets away. There's a chance," quipped Shanahan.
The 49ers secured Gregory through a trade deal with the Denver Broncos, relinquishing a sixth-round draft pick in 2024 in exchange for the veteran pass rusher and a 2024 seventh-round draft pick. The team released defensive end Kerry Hyder to make roster room.
San Francisco will officially announce its list of inactive players 90 minutes before kickoff. On Saturday, the 49ers elevated defensive lineman Austin Bryant and cornerback Kendall Sheffield from the practice squad for the Week 5 contest.
More San Francisco 49ers News
-
49ers QB Mac Jones trade? Graziano explains why Vikings may pass
The Minnesota Vikings are exploring options at quarterback as they look to create competition for J.J. McCarthy following a disappointing 2025 season. One name frequently linked to Minnesota has been Mac Jones of the San Francisco 49ers. Jones rejuvenated his NFL career this... -
Why the 49ers Should Seriously Consider Trading for Jonathan Greenard
The San Francisco 49ers have built their identity on defensive dominance. From their Super Bowl run in 2019 to recent NFC Championship appearances, the formula has been consistent: overwhelm opposing quarterbacks with relentless pressure. While Nick Bosa remains one of the... -
49ers Free Agency: Why Bradley Chubb Could Be the Missing Piece to a Dominant Pass Rush
The San Francisco 49ers are not rebuilding. They're competing for championships right now. When a team is firmly inside a Super Bowl window, hesitation becomes costly. Core players are in place. Expectations are clear. The margin for error shrinks. Contenders don't wait for... -
Why improvement in the 49ers secondary is imperative next season
The San Francisco 49ers' defense, under the guidance of defensive coordinator Robert Saleh, demonstrated resilience and flashes of brilliance throughout last season. However, the secondary's struggles became increasingly apparent, culminating in a playoff loss to the Seattle...