Ian Rapoport of NFL Media reports that Kittle will be a game-time decision, though, indicating that there remains a chance that the tight end will be suited up for this afternoon's action.
Kittle practiced on Friday. Although, he was limited. It was his first practice since suffering his groin strain on September 5.
Matt Maiocco of NBC Sports Bay Area reports that the 49ers' goal is to have Kittle available for the team's Week 3 contest against the Denver Broncos, making it unlikely we'll see the tight end on the field against Seattle.
"Looked awesome," head coach Kyle Shanahan said of his tight end's work on Friday.
The injury forced Kittle to miss the team's Week 1 matchup in Chicago against the Bears. Although, there was some hope that he could play in that matchup too.
"He's healthier seven days later than he was last week when he was questionable [to play in Week 1]," Shanahan said on Friday.
The 49ers and Seahawks kick off from Levi's Stadium today at 1:05 p.m. PT.