The status of offensive tackle Trent Williams remains the biggest question heading into the game. He suffered an ankle injury against the Green Bay Packers and is listed as "questionable" for Sunday after not practicing all week.
After Friday's practice, head coach Kyle Shanahan said that Williams remains hopeful that he will play against the Rams.
"He came out for walk-through today, and Trent's adamant that he's going," Shanahan said. "He was last time, too. I believe Trent when he says that he's going to do everything he can to play, so I'd be surprised if he doesn't. But I was surprised last time. I was also surprised he was able to finish the game versus Green Bay.
"So hopefully, his mindset will be how his body reacts on Sunday. We know it would help us a lot, but if not, we'll deal with it."
Shanahan was asked whether the offensive lineman is dealing with a high- or low-ankle sprain but was unwilling to provide an answer.
"Good question, though," Shanahan added.
Quarterback Jimmy Garoppolo is no longer bothered by his shoulder injury but is still playing through a painful thumb injury. On Sunday, he'll have an opportunity to lead his team to a Super Bowl appearance for the second time in three years.
"Feels great. Arm's ready to roll," Garoppolo said of his shoulder.
The only other player listed as "questionable" is running back Jeff Wilson Jr.
Below are the official injury reports for the 49ers and Rams, provided by the 49ers Communications staff. Also included are Friday's practice participation reports.
San Francisco 49ers
Questionable
T Trent Williams (ankle), RB Jeff Wilson (ankle)
Los Angeles Rams
Doubtful
T Joseph Noteboom (chest)
Questionable
WR Van Jefferson (knee), S Taylor Rapp (concussion)
San Francisco 49ers Friday Practice
Did Not Participate In Practice
T Trent Williams (ankle)
Limited Participation in Practice
RB Jeff Wilson (ankle)
Full Participation in Practice
DL Nick Bosa (not injury related - resting player), QB Jimmy Garoppolo (right thumb), C Alex Mack (not injury related - resting player), RB Elijah Mitchell (knee), CB Ambry Thomas (knee)
Los Angeles Rams Friday Practice
Did Not Participate In Practice
RB Cam Akers (not injury related - resting player), T Joseph Noteboom (chest)
Limited Participation in Practice
WR Van Jefferson (knee), S Taylor Rapp (concussion)
Full Participation in Practice
T Greg Gaines (toe), RB Buddy Howell (hamstring), T Andrew Whitworth (knee), QB John Wolford (illness)
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