The 49ers activated wide receiver Mohamed Sanu (knee) off of injured reserve, and he was out on the practice field preparing for the Rams.
Cornerback Ambry Thomas was inactive against the Green Bay Packers due to a bone bruise in his knee. He practiced but was limited.
Quarterback Jimmy Garoppolo, dealing with shoulder and thumb injuries, was a full participant. In fact, head coach Kyle Shanahan noted that the shoulder injury no longer appeared on his injury list.
"I hear about the thumb more than the shoulder, so that's off the injury report now," Shanahan said before practice. "So I guess we're good."
Tackle Trent Williams sustained an ankle injury against the Packers, leaving his status for Sunday unclear. The All-Pro offensive lineman didn't practice but isn't being ruled out.
"In Trent's mind, there's no way he's not playing," Shanahan said. "That's why he was so crushed last game (Week 18) because he believed he would, and his body wouldn't let him. So hopefully, we'll have some better luck this game. But I know he believes he's playing, and so do I. So, we'll see how that pans out as the week goes. If he can, he will."
Neither wide receiver Deebo Samuel nor tight end George Kittle appeared on the injury report, which means both were full participants in practice.
Below are Wednesday's practice participation reports for both the 49ers and Rams, which were provided by the 49ers Communications staff.
San Francisco 49ers Wednesday Practice
Did Not Participate In Practice
DL Nick Bosa (not injury related - resting player), C Alex Mack (not injury related - resting player), RB Elijah Mitchell (knee), T Trent Williams (ankle), RB Jeff Wilson (ankle)
Limited Participation in Practice
CB Ambry Thomas (knee)
Full Participation in Practice
QB Jimmy Garoppolo (right thumb)
Los Angeles Rams Wednesday Practice
Did Not Participate In Practice
T Greg Gaines (toe), WR Van Jefferson (knee), T Joseph Noteboom (chest)
Limited Participation in Practice
RB Buddy Howell (hamstring), S Taylor Rapp (concussion), T Andrew Whitworth (knee)
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