Linebackers Dre Greenlaw and Marcell Harris did not practice. Harris remains in the concussion protocol. Both sustained their injuries during Sunday's win over the Minnesota Vikings. Greenlaw has been ruled "out" while Harris is "questionable."
Running back Trey Sermon was also absent from practice due to the ankle injury suffered on Sunday.
"It's not [a high-ankle sprain], but it was a pretty bad one," head coach Kyle Shanahan said earlier this week before admitting that injured reserve is a possibility for the rookie running back. "He'll be out for a little while."
KNBR's Jake Hutchinson reports that linebacker Fred Warner was in uniform and working on a side field. On Monday, Shanahan stated that Warner would not play this weekend due to a hamstring strain but could return next week. On Friday, the 49ers officially listed as "doubtful," leaving the door open for the star linebacker to potentially play.
Wide receiver Deebo Samuel suffered a groin strain against the Vikings. He and fellow wideout Mohamed Sanu, who has been on injured reserve since November 15 due to a knee injury, were also seen working on a side field. They, however, were not in uniform. Samuel has been ruled "out" for Sunday.
On Friday, Shanahan added that defensive tackle Maurice Hurst has been ruled out after suffering a setback during Thursday's practice.
Below are the official injury reports for the 49ers and Seahawks, which were provided by the 49ers Communications staff. Also included are Friday's practice participation reports.
San Francisco 49ers
Out
LB Dre Greenlaw (groin), DL Maurice Hurst (calf), WR Deebo Samuel (groin), RB Trey Sermon (ankle)
Doubtful
LB Fred Warner (hamstring)
Questionable
LB Marcell Harris (concussion)
Seattle Seahawks
Doubtful
G Damien Lewis (elbow, nir-medical)
Questionable
RB Alex Collins (abdomen), RB Travis Homer (calf), RB Rashaad Penny (hamstring)
San Francisco 49ers Friday Practice
Did Not Participate In Practice
LB Dre Greenlaw (groin), LB Marcell Harris (concussion), DL Maurice Hurst (calf), WR Deebo Samuel (groin), RB Trey Sermon (ankle), LB Fred Warner (hamstring)
Full Participation in Practice
DL Nick Bosa (not injury related - resting player), RB JaMycal Hasty (ankle), C Alex Mack (not injury related - resting player), RB Elijah Mitchell (rib, finger), DE Kentavius Street (wrist), T Trent Williams (not injury related - resting player)
Seattle Seahawks Friday Practice
Did Not Participate In Practice
G Damien Lewis (elbow, nir-medical)
Limited Participation in Practice
RB Alex Collins (abdomen), WR DK Metcalf (foot), T Brandon Shell (shoulder)
Full Participation in Practice
LB Cody Barton (calf), G Kyle Fuller (ankle), RB Travis Homer (calf), G Gabe Jackson (knee), RB Rashaad Penny (hamstring), CB D.J. Reed (knee)
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