- LB Azeez Al-Shaair
- OL Aaron Banks
- DL Nick Bosa
- T Shon Coleman
- DL Dee Ford
- WR Jalen Hurd
- DT Javon Kinlaw
- TE George Kittle
- C Alex Mack
- RB Elijah Mitchell
- CB Emmanuel Moseley
- RB Raheem Mostert
- RB Trey Sermon
- CB Jason Verrett
- DB Jimmie Ward
- LB Fred Warner
- CB K'Waun Williams
- T Trent Williams
- S Tavon Wilson
The Niners added wide receiver Jauan Jennings to the list of those sidelined shortly after announcing the players above.
Sermon is dealing with an ankle injury.
The good news is that Deebo Samuel is expected to play. The wide receiver left practice on Friday with what head coach Kyle Shanahan described as a "tight glute." As of Friday night, Shanahan and the 49ers were awaiting the results of an MRI to determine the severity of Samuel's injury.
The 49ers and Chargers kick off at 4:30 p.m. PT from SoFi Stadium in Inglewood, California.
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