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- LB Azeez Al-Shaair
- OL Aaron Banks
- DL Nick Bosa
- T Shon Coleman
- DL Dee Ford
- WR Jalen Hurd
- DT Javon Kinlaw
- TE George Kittle
- C Alex Mack
- RB Elijah Mitchell
- CB Emmanuel Moseley
- RB Raheem Mostert
- RB Trey Sermon
- CB Jason Verrett
- DB Jimmie Ward
- LB Fred Warner
- CB K'Waun Williams
- T Trent Williams
- S Tavon Wilson
The Niners added wide receiver Jauan Jennings to the list of those sidelined shortly after announcing the players above.
Sermon is dealing with an ankle injury.
#49ers RB Trey Sermon is not playing because of ankle injury.
— Eric Branch (@Eric_Branch) August 22, 2021
The good news is that Deebo Samuel is expected to play. The wide receiver left practice on Friday with what head coach Kyle Shanahan described as a "tight glute." As of Friday night, Shanahan and the 49ers were awaiting the results of an MRI to determine the severity of Samuel's injury.
#49ers WR Deebo Samuel (glute) is expected to play vs. Chargers today after leaving practice early Friday.
— Eric Branch (@Eric_Branch) August 22, 2021
The 49ers and Chargers kick off at 4:30 p.m. PT from SoFi Stadium in Inglewood, California.
