Both wide receiver Deebo Samuel and running back Tevin Coleman are ruled out. Neither practiced this week. Two other receivers, River Cracraft and Trent Taylor, are listed as "questionable."
Sunday will be Samuel's third consecutive missed game due to a hamstring injury. He also missed the first three games of the season after suffering a Jones fracture in June.
Head coach Kyle Shanahan noted that cornerback Richard Sherman would not be activated from injured reserve before this weekend's game. The 49ers opened his practice windows this week. Sherman's most-likely return will be on November 29 after the bye week, against the Los Angeles Rams.
"He did a good job," Shanahan explained. "Was able to practice all three days on scout team. If we had to do it, we could push it, but it wouldn't be the smartest thing. So, we're going to take him into this bye week and feel good about him going against the Rams."
Below are the official injury reports for the 49ers and Saints, which were provided by the 49ers Communications staff. Also included are Friday's practice participation reports.
San Francisco 49ers
Out
RB Tevin Coleman (knee), LB Demetrius Flannigan-Fowles (hamstring), WR Deebo Samuel (hamstring), CB K'Waun Williams (ankle)
Questionable
WR River Cracraft (quadricep), WR Trent Taylor (back)
New Orleans Saints
Questionable
RB Dwayne Washington (back)
San Francisco 49ers Friday Practice
Did Not Participate In Practice
RB Tevin Coleman (knee), LB Demetrius Flannigan-Fowles (hamstring), WR Deebo Samuel (hamstring), CB K'Waun Williams (ankle)
Limited Participation in Practice
WR River Cracraft (quadricep)
Full Participation in Practice
WR Trent Taylor (back)
New Orleans Saints Friday Practice
Did Not Participate In Practice
RB Dwayne Washington (back)
Limited Participation in Practice
QB Drew Brees (right shoulder), C Erik McCoy (elbow)
Full Participation in Practice
T Ryan Ramczyk (back), WR Michael Thomas (ankle, hamstring)
Related News
More San Francisco 49ers News
-
Report: 49ers exploring possible relocation of practice facilities
The San Francisco 49ers have invested heavily in their current practice facility in Santa Clara, California, which sits adjacent to Levi's Stadium and serves as the team's headquarters. However, with limited room for expansion, only so much can be done. It turns out, the... -
49ers training camp report dates and joint practice dates announced
The NFL has announced official training camp report dates for all 32 teams, and the San Francisco 49ers will begin preparations for the 2026 season when rookies report on Saturday, July 18. Veterans will join the newcomers one week later, reporting to training camp on... -
49ers' Brandon Aiyuk criticizes NFLPA amid ongoing public feud
It appears Brandon Aiyuk's frustrations extend beyond his former agent and the San Francisco 49ers. On Sunday, the disgruntled wide receiver turned his attention to the NFL Players Association (NFLPA), adding another chapter to his increasingly public and reputation-damaging... -
49ers fans take note: NFL insider warns 'the 18-game slate is coming'
San Francisco 49ers fans would undoubtedly welcome another opportunity each season to watch their favorite team take the field. According to one NFL insider, that extra game is likely on the horizon—it's simply a matter of when the league and players can agree on the...