The 49ers last wore the uniforms during a Week 17 road matchup against the Seattle Seahawks last season. San Francisco won the game 26-21 in dramatic fashion. Before that, the 49ers wore the throwbacks during a 51-13 Week 8 rout of the Carolina Panthers.
The uniforms are replicas of those worn by the last 49ers team to win a Super Bowl — the 1994 squad that beat the San Diego Chargers in Super Bowl XXIX. Those uniforms were part of the league's 75th anniversary and were a throwback themselves to the team's jerseys during the 1955 season.
Sunday's primetime matchup will be the first time this season that San Francisco has donned the fan-favorite throwbacks. The team introduced the alternate uniforms in 2018 during that offseason's State of the Franchise event.