Cardinals head coach Kliff Kingsbury said Friday that Johnson's availability for Sunday would be a game-time decision. It looks like the ankle injury that limited him to three snaps last week against the New York Giants won't be fully recovered until after Thursday's meeting with San Francisco.
"He tried to go (back in against the Giants)," Kingsbury said this past week, "tried to tough it out and wasn't himself and didn't feel good. We want to make sure he feels like himself and 100 percent before we put him out there."
Chase Edmonds is expected to be the primary running back in place of Johnson. He carried the football 27 times for 126 yards with three touchdowns in the Cardinals' 27-21 win over the Giants last weekend.
Arizona signed running backs Alfred Morris, who spent last season with San Francisco, and Zach Zenner on Wednesday.
In the meantime, the Cardinals look to get above .500 against the Saints on Sunday while the 49ers look to remain undefeated against the Carolina Panthers.
Related News
More San Francisco 49ers News
-
Seahawks expected 49ers to target a running back early in the draft
The San Francisco 49ers drew criticism for selecting running back Kaelon Black in the third round of the 2026 NFL Draft. Few analysts projected Black to go that high, and even fewer viewed running back as a top priority for San Francisco entering the draft. However, one NFC... -
49ers waiting game with Brandon Aiyuk leaves NFL teams on hold
Why haven't the San Francisco 49ers traded disgruntled wide receiver Brandon Aiyuk yet? ESPN's Dan Graziano offered insight into the situation on Tuesday, pointing to what many around the NFL already believe—that Aiyuk will likely be released before the 2026 season. "We're... -
49ers star George Kittle shares hilarious story about early-morning heroics
San Francisco 49ers tight end George Kittle is apparently a hero—at least in the eyes of his wife, Claire. On Wednesday, Kittle shared a humorous story on social media detailing his latest act of bravery: eliminating a spider that invaded their home in the middle of the... -
Daniel Jeremiah ranks 49ers draft value last among NFL teams
NFL Media draft analyst Daniel Jeremiah ranked all 32 NFL draft classes based on the value each team received from its selections, and the San Francisco 49ers landed at the bottom of the list at No. 32. Jeremiah's rankings were based on where each player appeared within his...