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Marquise Goodwin, who was listed as questionable with hamstring and quad injuries on Friday's injury report, will not play against Arizona, according to a report from Adam Schefter of ESPN.
Goodwin has five receptions for 54 yards with a touchdown through three game appearances this season.
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Head coach Kyle Shanahan said on Friday that Goodwin's status would be a game-time decision and placed his chances of playing at about 50/50.
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