Mabin entered the league with the Tampa Bay Buccaneers as an undrafted free agent out of Iowa on May 1. Following his release seven days later, he was signed by the Bills on June 1 and then waived on September 12 before joining Buffalo's practice squad. Mabin was promoted to the active roster on October 7 and made his NFL debut during Week 5 against the Cincinnati Bengals and had one pass defensed. He was waived on Monday.
Wick entered the league with the Detroit Lions as an undrafted free agent out of Incarnate Word (Tex.) on May 6, 2016. He appeared in six games last season and had two receptions for 18 yards before being placed on injured reserve. He was signed to the Lions' practice squad on September 3 and then released three days later.
The 49ers 10-player practice squad now consists of the following players:
- WR DeAndre Carter
- OL John Flynn
- DL Jeremy Liggins
- CB Greg Mabin
- RB Jeremy McNichols
- QB Nick Mullens
- T Pace Murphy
- WR DeAndre Smelter
- TE Cole Wick
- OL Darrell Williams Jr.
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