Foster is still recovering from a high-ankle sprain he suffered during Week 1 against the Carolina Panthers. Reid is recovering from a PCL injury he suffered during Week 2 against the Seattle Seahawks.
Linebacker NaVorro Bowman, defensive end Elvis Dumervil, and tackle Joe Staley were each given a veteran's day off.
Two 49ers running backs were limited during Wednesday's practice. The team is being cautious with Carlos Hyde, who is recovering from a hip injury, and Matt Breida, who has an ankle injury.
Below are the official Wednesday practice participation reports for both the 49ers and Colts, as provided by the 49ers Communications team.
San Francisco 49ers Wednesday Practice
Did Not Participate In Practice
LB Navorro Bowman (not injury related), S Adrian Colbert (hamstring), DE Elvis Dumervil (not injury related), LB Reuben Foster (ankle), S Eric Reid (knee), T Joe Staley (not injury related), LB Dekoda Watson (groin)
Limited Participation in Practice
RB Matt Breida (ankle), WR Marquise Goodwin (concussion), RB Carlos Hyde (hip)
Full Participation in Practice
DE Pita Taumoepenu (ankle)
Indianapolis Colts Wednesday Practice
Did Not Participate In Practice
S Matthias Farley (quadricep), CB Nate Hairston (quadricep), WR Chester Rogers (hamstring)
Limited Participation in Practice
TE Jack Doyle (concussion), QB Andrew Luck (right shoulder), CB Rashaan Melvin (hamstring, ankle), CB Quincy Wilson (knee)
Full Participation in Practice
C Ryan Kelly (foot), RB Marlon Mack (shoulder), CB Chris Milton (hamstring), LB Anthony Walker (hamstring)
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