TE Vernon Davis and RB Frank Gore injured

Every game is a home game for the 49ers, and it's both by design and 30 years in the making. Late last month, the 3-win San Francisco 49ers headed south to face the 3-win Los Angeles Rams in a pivotal NFC West matchup. The Niners' fourth victory of the 2022 NFL regular season was abnormal on numerous fronts, highlighted by a "Trifecta" performance by San Francisco's new running back Christian McCaffrey, who threw a first-half touchdown pass before scoring on the ground and through the air in the second half. The Rams had no answer for McCaffrey or quarterback Jimmy Garoppolo, who played his best game of the season, as he led the 49ers

The San Francisco 49ers improved their record to 6-4 after a 38-10 win against the Arizona Cardinals in Week 11. Today, Pro Football Focus released its grades from the game. Which Niners played well, and who has more work to do? Below are Pro Football Focus' five highest-graded 49ers players on offense against the Cardinals. Trent Williams, LT, 94.4, 51 snaps George Kittle, TE, 89.8, 43 snaps Elijah Mitchell, RB, 85.7, 13 snaps Daniel Brunskill, RG, 80.0, 27 snaps Christian McCaffrey, RB, 79.9, 38 snaps Below are the five highest-graded 49ers players on defense. Charles Omenihu, DE, 84.6, 41 snaps Dre Greenlaw, LB, 82.3, 58 snaps Deommodore Lenoir, CB, 79.7, 68

Kyle Shanahan was feeling good on Monday night. The head coach's San Francisco 49ers won their third consecutive game, with the latest being a 38-10 victory over the Arizona Cardinals in an international matchup in Mexico City. The 49ers are getting hot, and have become a favorite to make some noise down the stretch and in the NFC playoffs, assuming things continue to trend upward for the team. "I felt real good about the guys," Shanahan told reporters after the game. "[The players] had a great week of practice. They've really been gelling these last three weeks. I feel like it's gotten a little better each week, and it was nice to put a full game together today." Players are also feeling the momentum build up. "We're definately ready to

The San Francisco 49ers were clicking on all cylinders in a 38-10 throttling of a hapless Arizona Cardinals team in Mexico City on Monday night football. The Niners are again favored by more than a touchdown as they return home on a short week to welcome another bottom-dwelling team in the New Orleans Saints. Here we discuss the odds and analysis from a betting perspective. When: Sunday November 27th, 2022 at 1:25pm (FOX) Where: Levi's Stadium, Santa Clara, California Line: 49ers -9; o/u 43 New Orleans Saints The New Orleans Saints handled a reeling Los Angeles Rams team who were without Cooper Kupp and down Matthew Stafford leaving with a concussion. Andy Dalton tossed 3 touchdowns on 21-25 passing for 260 yards and Chris