Crabtree to come off PUP soon?

49ers Twitter and Facebook are melting down. All it took was one ugly loss, and many fans have already turned on the coaching staff, and the young quarterback, while declaring the season over. It's funny and annoying altogether. It's also way too early for any of that. This week, considering the frustration that many fans were experiencing, we decided to not only answer questions in this mailbag, but also give fans the chance to vent. Several did. But we only have room for so many. So here we go. Let's get to the mailbag. Does it seem that when the defense crumbles it's because of a needless penalty by Greenlaw? How many more are acceptable before a change is made? - Niner Jim The defense was dominant in the first half. And for the

The San Francisco 49ers are playing the Seattle Seahawks at Levi's Stadium. It is the Niners' home opener. The team entered the matchup without tight end George Kittle and offensive lineman Daniel Brunskill. The former is dealing with a groin strain, while the latter is attempting to return from a hamstring injury. Both are among five inactive players for the 49ers. Below are the 49ers-Seahawks in-game injury updates. QB Trey Lance (ankle, ruled out) Jimmy Garoppolo entered the game for injured quarterback Trey Lance, who went down late in the first quarter. Lance was carted off the field after sustaining what appeared to be a lower right leg injury.

Congratulations to the San Francisco 49ers at Levi's Stadium during Sunday's 27-7 victory over the Seattle Seahawks. Linebacker Fred Warner believes you played a significant role in helping the team overcome the devastating loss of a teammate and earning its first win of the season. The linebacker loved the element that the home crowd brought to the game. "Huge. Huge, huge, huge," Warner said after the game. "I mean, I've been a part of some pretty loud games. That one was super loud from the start to the finish. I was so happy to be back home in front of our fans. "It's The Faithful. They call them The Faithful for a reason, so it was super fun to be back out there." The 49ers welcomed a return to Levi's Stadium after a disappointing and unexpected