Maybe heading into games as underdogs is good luck for the San Francisco 49ers. Kyle Shanahan's squad has been in that position over the last two games and has won each. That is the case again for San Francisco's Week 8 matchup against the Seattle Seahawks.
Seattle opened as 3.5-point favorites (O/U 53.5) over San Francisco in the upcoming matchup at CenturyLink Field, according to BetMGM. The Seahawks own a 5-1 record while the 49ers sit at 4-3.
San Francisco is coming off an impressive 33-6 road win over the New England Patriots that saw the offense rack up 467 total yards of offense, including 197 rushing yards. The team hopes to remain undefeated on the road.
"We're in a good spot right now," quarterback Jimmy Garoppolo said after the game. "We're playing well, all three phases. We're playing together. I think it's just a mindset that we have as a group. You can feel it. I felt it in the locker room today from the guys; felt it all week in practice. It's a good feeling when you're in the groove. We've just got to keep this thing going and keep stacking [wins]."
The injuries keep piling up for the 49ers, though. The team likely lost another running back after Jeff Wilson Jr. suffered an ankle injury — feared to be a high-ankle sprain — on a touchdown run. Head coach Kyle Shanahan expects second-year wide receiver Deebo Samuel to miss "some time" with a hamstring injury.
"Hopefully, the severity won't be too bad, and he won't miss too much time," Shanahan added.
Meanwhile, Seattle is coming off a frustrating 37-34 overtime loss to the Arizona Cardinals. While quarterback Russell Wilson threw for 388 yards with three touchdowns, he also threw three interceptions, including a costly one in overtime that set up Arizona to kick a game-winning field goal.
"I thought we played a great game except for those three plays, honestly," Wilson said after the loss. "Those are my fault. There's so much that we can do, and we have so much confidence. Our confidence is not going to waver. They're a great football team, too. We knew it was going to be a battle. ... I have to be better, which I'm looking forward to."
Wilson also led the Seahawks with 84 rushing yards on six attempts.
The 49ers and Seahawks are scheduled to kick off on Sunday, November 1 at 1:25 p.m. PT.