Bush's ACL is reported to be fine.
Bush slipped on the sideline concrete at the Edward Jones Dome while running out of bounds on a punt return. He did not get back up and was eventually carted to the locker room. He was on crutches in the locker room following the game.
RB Mike Davis will have surgery on his fractured hand on Tuesday as well. RB Carlos Hyde missed Sunday's game against the St. Louis Rams to rest what is believed to be a fractured foot. Although, Ryan Sakamoto of NinerFans.com believes he may require surgery as well.
On Monday, the 49ers signed former Cleveland Browns RB Shaun Draughn. They also signed RB Jarryd Hayne, who the team waived on Saturday, to the practice squad. Although, it is possible Hayne gets elevated to the 53-man roster once Bush is placed on IR.
On Monday, the team also traded TE Vernon Davis to the Denver Broncos.
More San Francisco 49ers News
Mock Draft Roundup: Final projections have the 49ers going in several directions Anthony "Spice" Adams to announce 49ers' draft picks in 2nd and 3rd rounds George Kittle's message to Brandon Aiyuk amid contract talks with 49ers: "Be patient" Report: Several teams inquiring about 49ers' Deebo Samuel and Brandon Aiyuk