He was carted off the field with a left leg injury and is questionable to return to the game.
Bush was an offseason free agency acquisition and was backing up starter Carlos Hyde. His departure from the game makes Jarryd Hayne the backup.
The Vikings recovered a Hayne fumble on his first NFL career punt return. Hyde and Hayne are the only other running backs in uniform tonight.
Update:
More San Francisco 49ers News
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49ers roster moves: D-lineman signed while another is placed on IR
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Patrick Willis gives stamp of approval to 49ers rookie linebacker
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Why 49ers' Kyle Shanahan refused to name players who stood out vs. Raiders
A few San Francisco 49ers players made positive impressions on head coach Kyle Shanahan during Thursday night's preseason win over the Las Vegas Raiders. However, Shanahan opted to remain tight-lipped about his personnel evaluations, giving reporters little insight into his... -
49ers' Kyle Shanahan shifts focus to regular season: "It's going to get real, real fast"
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