He was carted off the field with a left leg injury and is questionable to return to the game.
Bush was an offseason free agency acquisition and was backing up starter Carlos Hyde. His departure from the game makes Jarryd Hayne the backup.
The Vikings recovered a Hayne fumble on his first NFL career punt return. Hyde and Hayne are the only other running backs in uniform tonight.
Update:
More San Francisco 49ers News
-
49ers' Kyle Shanahan explains Brock Purdy's remarkable success in Seattle
San Francisco 49ers quarterback Brock Purdy earned his first career road start in 2022 with a 21-13 win over the Seattle Seahawks at Lumen Field. Since then, he has played three additional games in one of the loudest and most challenging environments in the NFL — and won all... -
How Eric Kendricks became an instant force multiplier for the 49ers defense
When a veteran signs with an NFL team late in the season, it's often as a break-glass-in-case-of-emergency option—a short-term fix after injuries pile up. That may have been the initial expectation when the San Francisco 49ers signed linebacker Eric Kendricks in November.... -
49ers vs. Seahawks: Keys to Victory and a Trip to the NFC Championship Game
What's going on, Faithful? It's your boy Wayne Breezie, and we're right back at it with everything on the line. The San Francisco 49ers are headed into hostile territory to take on the Seattle Seahawks, the 2025 NFC West champions, with a trip to the NFC Championship Game on... -
49ers QB Brock Purdy '100 percent' confident team can win Super Bowl next season
Despite his team looking like anything other than a Super Bowl contender in their 41-6 Divisional Round playoff loss to the Seattle Seahawks on Saturday night, San Francisco 49ers quarterback Brock Purdy seems extremely high on his team's chances as they head into 2026. Purdy...