The 49ers are coming off of a 26-0 win over the St. Louis Rams while the Cardinals are coming off of a 19-13 win over the Dallas Cowboys.
The game kicks off at 1:05 PM and, as usual, you can visit 49erswebzone.com for the latest news and updates during and after the game.
The game will be televised on FOX.
The 49ers are 3.5 point favorites.
In the 49erswebzone.com Pick 'Em Contest, 98% of 49ers fans believe that the 49ers will win this game.
Within Sportstacular, a popular mobile phone scores application, 90% of fans believe that the 49ers will win this game.
You can follow the game live on NFL.com's Game Center.
You can also discuss the game with fans in the 49erswebzone.com forums.
More San Francisco 49ers News
-
Arizona State DB describes recent meeting with 49ers as "really good"
Former Arizona State defensive back Myles Rowser recently spoke with Justin Melo of Sports Illustrated and confirmed that he met with all 32 NFL teams during the East-West Shrine Bowl in January. Among those conversations, his meeting with the San Francisco 49ers stood out. "I... -
49ers Free Agency: 3 Moves San Francisco Must Make to Stay in the Super Bowl Window
The San Francisco 49ers are entering another critical offseason, and free agency could determine whether this team remains firmly in the Super Bowl conversation or takes a step back in the NFC. The roster still has elite talent. The coaching staff remains intact. The... -
49ers draft philosophy: Why San Francisco must chase "handfuller" talent
I hate the term unicorn player. There has never been anyone who was truly one of a kind. I also hate it when commentators say a player has a "unique skill set"—for the same reason. My term is "a handfuller." What that means is that, historically, there have been only a... -
49ers WR Kendrick Bourne signing with Cardinals in free agency
Wide receiver Kendrick Bourne is staying in the NFC West—unfortunately for the San Francisco 49ers, it's with a division rival. NFL insider Jordan Schultz reports that the Arizona Cardinals are signing Bourne to a two-year deal worth up to $12 million. Sources: The...