The game kicks off at 5:30 pm and as usual, you can visit 49erswebzone.com for the latest news and updates during and after the game.
Within our NFL Pick 'em Contest, 41% of fans believe that the 49ers will win this game.
Within Sportstacular, a popular mobile phone scores app, 20% of fans believe that the 49ers will win this game.
You can follow the game live on NFL.com's Game Center.
You can also discuss the game with fans in the 49erswebzone.com forums.
More San Francisco 49ers News
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Tyreek Hill to the 49ers? San Francisco named a top fit for All-Pro WR
The Miami Dolphins have moved on from wide receiver Tyreek Hill, releasing the veteran nearly five months after he suffered a significant knee injury. Hill underwent surgery to repair the damage, and his agent, Drew Rosenhaus, has previously stated that the goal is for the star... -
49ers draft buzz: Daniel Jeremiah identifies pass rushers, WR targets for San Francisco
With the 2026 NFL Draft approaching, Daniel Jeremiah offered insight into how the San Francisco 49ers could address two of their most pressing offseason needs: pass rusher and wide receiver. The longtime NFL Draft analyst held his annual pre-Combine conference call ahead of... -
49ers offensive line rankings: How PFF graded San Francisco's starters in 2025
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49ers free agency: CBS Sports urges San Francisco to target Joey Bosa
The San Francisco 49ers' pass rush was a major weakness in 2025. The defense totaled just 20 sacks — the fewest in the NFL — creating an urgent need for reinforcements this offseason. If new defensive coordinator Raheem Morris is going to stabilize the unit in his first...