The last time the two teams met, quarterback Brett Favre broke the collective hearts of 49ers fans everywhere with his touchdown in the final seconds that put the Vikings on top giving them the 27-24 win.
Favre will play against the 49ers for about 10 snaps and it will be his first action of the season after announcing that he would not be retiring.
The game will be broadcast live on Sunday Night Football at 5:00 pm.
You can also follow the game live on NFL.com's Game Center.
You can also discuss the game with fans in the 49erswebzone.com forums and chat room.
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