Although the 49ers have not completely ruled out Bosa for Sunday's game, their final contest before the bye week, Matt Zenitz of CBS Sports reports a "high level of optimism" that the defensive end will return for San Francisco's Week 9 matchup against the Las Vegas Raiders on November 8 at Levi's Stadium.
It's unclear whether Zenitz's report suggests that Bosa has been completely ruled out for Week 7. However, his absence from practice this week makes that a distinct possibility.
Bosa is in his eighth NFL season. Before suffering the calf injury, he recorded seven tackles, two tackles for loss, and one quarterback hit in two appearances.
The 49ers have one more practice scheduled for Friday before traveling to Atlanta for Sunday's matchup against the Falcons.
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