"Two league sources say that the San Francisco 49ers are among the teams that have made contact with Dallas," Harris wrote.
H/t to Charean Williams of Pro Football Talk for highlighting the report.
The Pro Football Talk writer also noted a connection between the teams. The 49ers hired former Cowboys defensive coordinator Matt Eberflus as their assistant head coach of defense this offseason.
"Odighizuwa signed a four-year, $80 million contract last offseason before the Cowboys traded for defensive tackles Kenny Clark and Quinnen Williams," Charean Williams wrote. "On Tuesday, they signed nose tackle Otito Ogbonnia."
According to OverTheCap.com, Odighizuwa is scheduled to carry a $20.75 million salary-cap hit in 2026.
The Cowboys selected Odighizuwa (6-2, 280) in the third round (75th overall) of the 2021 NFL Draft out of UCLA. He has spent his entire NFL career in Dallas, serving as a primary starter along the interior defensive line since his rookie season.
During the 2025 season, Odighizuwa appeared in all 17 games, making 13 starts. He recorded 44 tackles and 28 assists while adding 3.5 sacks and 23 quarterback hits, helping anchor the middle of the Cowboys' defensive front.
Through five NFL seasons, Odighizuwa has appeared in 84 games with 76 starts, totaling 216 tackles, 17.0 sacks, and 34 tackles for loss. He has also registered 81 quarterback hits, two forced fumbles, and one pass defensed.
Related News
More San Francisco 49ers News
-
49ers vs. Cowboys injury report: 2 starting corners continue to miss practice
The San Francisco 49ers are preparing for their Week 10 contest against the Dallas Cowboys on Sunday at AT&T Stadium in Arlington, Texas. San Francisco's two starting cornerbacks, Deommodore Lenoir and Renardo Green, continue to miss practice with injuries. Lenoir is... -
49ers vs. Cowboys injury report: Deebo Samuel returns; 6 players miss practice
The San Francisco 49ers are preparing for their Week 10 contest against the Dallas Cowboys on Sunday at AT&T Stadium in Arlington, Texas. Wednesday was wide receiver Keenan Allen's first practice since being traded from the Indianapolis Colts to the 49ers. Keenan Allen... -
49ers vs. Cowboys final injury report: Trent Williams, 4 CBs questionable for Week 10
The San Francisco 49ers are preparing for their Week 10 contest against the Dallas Cowboys on Sunday at AT&T Stadium in Arlington, Texas. Both teams have released their official injury reports, which are provided below. San Francisco 49ers Out WR Mike Evans... -
49ers Threat Report: 3 Cowboys Who Could Pose Major Problems in Week 10
The San Francisco 49ers head to Dallas in Week 10 for a matchup against a Cowboys team with plenty of offensive firepower and one of the NFL's most disruptive interior defenders. For San Francisco, the challenge starts with CeeDee Lamb. Dak Prescott has been playing efficient...