Players are listed in order of most recent report.
CB Upton Stout (concussion, out)
Upton Stout exited late in the third quarter and headed to the medical tent for evaluation before later going to the locker room. Chase Lucas replaced him.
The 49ers announced that Stout is being evaluated for a concussion and has been ruled out.
LT Trent Williams (hamstring, out)
Trent Williams exited early in the first quarter and was replaced by Austen Pleasants. The 49ers initially announced that Williams was questionable to return with a hamstring injury. However, the team ruled him out at the start of the second half.
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