Previous game
The 49ers entered their bye week coming off a 26-8 victory over the Cleveland Browns. Offensively, the team was led by RB Christian McCaffrey, who logged 20 carries for 53 yards and a rushing touchdown, along with four receptions for 21 yards. WR Jauan Jennings added four catches for 39 yards and a touchdown, while QB Brock Purdy completed 16 of 29 pass attempts for 168 yards and scored once on the ground.
Defensively, the 49ers totaled 3.0 sacks of Browns QB Shedeur Sanders and held Cleveland to just 115 passing yards. DL Clelin Ferrell delivered a standout performance, recording a career-high nine tackles and 2.0 sacks. DL Keion White added three tackles and a sack, while S Malik Mustapha contributed seven tackles and a pass defensed. LB Luke Gifford also registered his first fumble recovery of the season.
On special teams, WR Skyy Moore recorded three punt returns for 69 yards, including a career-long 66-yard return. CB Darrell Luter Jr. added the first special teams fumble recovery of his career on a muffed Browns punt.
Below is everything you need to know to follow the upcoming game.
When does the game start?
Sunday, December 14 at 1:25 p.m. PT
Where is the game being played?
Levi's Stadium in Santa Clara, California
Who are the head coaches?
49ers: Kyle Shanahan
Titans: Mike McCoy
Betting Odds
As of December 10, the 49ers are favored by 12.5 points in this game, with an over/under of 44.5 points, per BetMGM.
What channel is the game on?
Network: FOX
Play-By-Play: Adam Amin
Color Analyst: Drew Brees
Sideline Reporter: Kristina Pink
Viewers outside the broadcast area can watch the game via NFL Sunday Ticket on YouTube TV or YouTube Premium, but a subscription to the package is required.
What areas will receive the broadcast?
The broadcast will be viewable within the markets designated below for those without NFL Sunday Ticket.
Coverage map courtesy of 506sports.com
Where can I stream the game?
NFL Sunday Ticket subscribers can stream the game using the YouTube TV app. Those who purchased through YouTube Premium can watch via the YouTube app. Additionally, NFL+ subscribers can stream the game in its entirety once the matchup has been completed.
Bay Area fans can stream the game through the official 49ers app or at 49ers.com.
Where can I listen to the radio broadcast?
49ers Radio
Bay Area fans can listen on KGO 810 AM and The Bone 107.7 FM, where Guy Haberman and Tim Ryan will call the game.
Jesús Zárate and Carlos Yustis will call the game in Spanish. Fans can listen at 49ers.com/esp.
Titans Radio
Fans in the Tennessee area can listen on WGFX 104.5 The Zone, where Taylor Zarzour and Dave McGinnis will call the game.
Streaming
NFL+ subscribers can listen to the game through that service.
Game discussion
Fans can discuss the game within our Niner Talk forum.
How has this series played out historically?
Matchups: 15
Series Record: 49ers lead series 9-6
49ers Home Record vs. Titans: 49ers lead series 4-3
49ers Away Record vs. Titans: 49ers lead series 5-3
First Meeting: 11/15/70, 49ers win 30-20, at Hou.*
Last Meeting: 12/23/21, Titans win 20-17, at Ten.
Current Streak: Lost 1
Longest 49ers Win Streak: 4 (12/13/81 – 10/7/90)
Longest Titans Win Streak: 2 – 2 times (Last 11/27/05 – 11/8/09)
Most 49ers Points: 34 (10/21/84): 49ers win 34-21, at Hou.
Most Titans Points: 34 (11/8/09): Titans win 34-27, at SF
49ers Shutouts: None
Titans Shutouts: None
* Houston Oilers
49ers Notes
- QB Brock Purdy passed for 168 yards and a touchdown and recorded his first rushing touchdown of the season in Week 13. He has a touchdown pass and 150+ passing yards in all five games he has played this season.
- RB Christian McCaffrey totaled 74 scrimmage yards (53 rushing, 21 receiving) and a rushing touchdown in Week 13. He has 849 rushing yards and 806 receiving yards in 2025 and is one of two players in NFL history (along with Hall of Famer Marshall Faulk) with 800+ rushing yards and 800+ receiving yards in three career seasons. He is the third player in NFL history (Hall of Famer LaDainian Tomlinson – six seasons, Shaun Alexander – five) with 1,600+ scrimmage yards (1,655) and 13+ touchdowns (13) in five career seasons. He ranks third in the NFL with 1,655 scrimmage yards and fifth with 85 receptions in 2025. He aims for his fourth straight game with a rushing touchdown. He had 146 rushing yards and three touchdowns (two rushing, one receiving) in his last game vs. Tennessee (11/3/19 with Carolina).
- WR Jauan Jennings had a touchdown reception in Week 13 and has a receiving touchdown in four of his past five games.
- TE George Kittle led the team with 67 receiving yards in Week 13 and aims for his fifth straight game with 65+ receiving yards. He is tied for sixth among tight ends with five touchdown catches in 2025. Since 2017, he has 7,776 receiving yards and 50 touchdown receptions, making him the fifth tight end in NFL history with 7,500+ receiving yards and 50+ receiving touchdowns in his first nine seasons.
- LB Dee Winters had six tackles in Week 13 and has five or more tackles in five of his past six games. He has a tackle for loss in three of his past four home games.
- LB Tatum Bethune has 10+ tackles in five of his past six games.
- DE Clelin Ferrell led the team with nine tackles and two sacks in Week 13. He aims for his third straight game with a sack.
- DE Keion White recorded his first full sack of the season in Week 13.
- CB Upton Stout (rookie) had seven tackles and a tackle for loss in Week 13 and aims for his fourth straight game with six or more tackles.
- S Ji'Ayir Brown aims for his third straight home game with a pass defensed. He has five or more tackles in three of his past four games.
- S Malik Mustapha recorded seven tackles, a tackle for loss, and a pass defensed in Week 13. He has seven or more tackles in three of his past four games and aims for his third straight game with a tackle for loss.
Titans Notes
- QB Cam Ward passed for 117 yards and two touchdowns in Week 14. He leads all rookies in passing yards (2,468) and ranks second in touchdown passes (9). He has a touchdown pass in three of his past four games and aims for his fourth straight road game with a touchdown pass.
- RB Tony Pollard led the team with a career-high 161 rushing yards and added two rushing touchdowns last week. He aims for his third straight game with 60+ rushing yards.
- RB Tyjae Spears totaled 47 scrimmage yards (28 receiving, 19 rushing) in Week 14. He has 45+ scrimmage yards in five of his past six road games.
- WR Chimere Dike (rookie) recorded a touchdown catch last week and has a receiving touchdown in two of his past three games. He aims for his third straight road game with five or more receptions.
- WR Elic Ayomanor (rookie) had a touchdown catch in Week 14.
- TE Chig Okonkwo has 45+ receiving yards in three of his past four road games.
- DT Jeffery Simmons recorded seven tackles, two tackles for loss, 1.5 sacks, and a pass defensed last week. He has a sack in three of his past four games and aims for his sixth straight road game with a sack and his third straight overall with six or more tackles.
- LB Cody Barton had five tackles and three passes defensed in Week 14. He aims for his fourth straight road game with a pass defensed and his fourth straight game against San Francisco with 10+ tackles. He posted 12 tackles and a tackle for loss in his last game vs. the 49ers (12/31/23 with Washington).
- LB Cedric Gray led the team with 10 tackles and added a fumble recovery last week. He aims for his sixth straight game with seven or more tackles.
- LB Arden Key recorded three tackles in Week 14. He previously posted 22 tackles, 6.5 sacks, five tackles for loss, and a pass defensed in 2021 with San Francisco.
- S Amani Hooker had six tackles last week. He recorded six tackles and an interception in the last meeting.
- S Xavier Woods posted three tackles and an interception in Week 14. He had six tackles and a pass defensed in his last game vs. San Francisco (11/28/21 with Minnesota).
- S Kevin Winston (rookie) had five tackles, two tackles for loss, and two passes defensed last week. He aims for his fifth straight game with five or more tackles.
- CB Marcus Harris (rookie) recorded four tackles and his first career forced fumble in Week 14.
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