San Francisco 49ers
Out
- C Jake Brendel (hamstring)
- DE Yetur Gross-Matos (knee, hamstring)
- DE Bryce Huff (hamstring)
- WR Ricky Pearsall (knee)
- QB Brock Purdy (toe)
Questionable
- T Spencer Burford (knee)
- LB Luke Gifford (hamstring)
- CB Deommodore Lenoir (quadricep)
Houston Texans
Out
- WR Nico Collins (concussion)
- CB Alijah Huzzie (knee)
- WR Christian Kirk (hamstring)
Questionable
- DE Denico Autry (knee)
- CB Jaylin Smith (hamstring)
Injury Notes
Quarterback Brock Purdy continues to be a limited practice participant as he works his way back from the toe injury suffered in Week 1. However, he has been ruled out for Sunday, leaving Mac Jones set to make his sixth start of the season.
Shanahan noted that Purdy will travel with the 49ers this weekend, a positive sign of progress in his recovery.
Wide receiver Ricky Pearsall has not played or practiced since Week 4. He has been dealing with a knee injury and is also ruled out for the Texans game.
After not practicing on Wednesday or Thursday due to a quadriceps injury, cornerback Deommodore Lenoir returned on Friday. Linebacker Luke Gifford, who also did not practice on Thursday, was back on the field. Both are questionable for Sunday.
Below are Friday's practice participation reports for both the 49ers and Texans, which were provided by the 49ers Communications staff.
San Francisco 49ers Friday Practice
Did Not Participate In Practice
- C Jake Brendel (hamstring)
- DE Yetur Gross-Matos (knee, hamstring)
- DE Bryce Huff (hamstring)
- WR Ricky Pearsall (knee)
Limited Participation in Practice
- T Spencer Burford (knee)
- LB Luke Gifford (hamstring)
- CB Deommodore Lenoir (quadricep)
- QB Brock Purdy (toe)
Full Participation in Practice
- DT Kalia Davis (hand)
- CB Renardo Green (toe)
- WR Jauan Jennings (ankle, rib, shoulder)
- QB Mac Jones (knee, oblique)
- RB Christian McCaffrey (not injury related - resting player)
- CB Upton Stout (ankle)
- DT C.J. West (thumb)
- T Trent Williams (not injury related - resting player)
Houston Texans Friday Practice
Did Not Participate In Practice
- DE Denico Autry (knee)
- WR Nico Collins (concussion)
- WR Christian Kirk (hamstring)
Full Participation in Practice
- DE Derek Barnett (ankle)
- TE Brenden Bates (wrist)
- CB Alijah Huzzie (knee)
- TE Dalton Schultz (back, shoulder)
- CB Jaylin Smith (hamstring)
- DE Darrell Taylor (illness)
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