Right guard Dominick Puni left the game during the starters' lone drive and did not return.
"Dominick Puni left with a knee, never returned," Shanahan told reporters. "It'll be a few weeks—possible PCL."
The coach isn't dismissing the possibility that Puni could suit up for the first game of the regular season. Obviously, we've seen the last of the second-year offensive lineman during the preseason.
Two running backs also exited the game. Patrick Taylor suffered a dislocated shoulder and is expected to miss a "couple of weeks," while Corey Kiner sustained a high-ankle sprain and will miss multiple weeks.
The injuries add to a growing list of setbacks the 49ers have dealt with throughout training camp, putting pressure on the team's depth.
"You just deal with it," Shanahan said. "Hopefully, we'll get a bunch of guys back here. I mean, we didn't lose anyone for the year or anything like that. And we had pretty good luck on defense and special teams today, so that was good."
Shanahan added: "Losing those three guys on offense was tough, but they won't be out forever, so hopefully, they'll heal up fast."
The 49ers now turn their attention to their final preseason matchup, a home game against the Los Angeles Chargers at Levi's Stadium. After that, Shanahan and his team will prepare for their Week 1 divisional showdown against the Seattle Seahawks at Lumen Field.
Related News
More San Francisco 49ers News
-
Brandon Aiyuk Revenge Game? Ranking the 49ers' 2026 Trap Games
Aiyuk's aggressive push toward Washington leads straight back to Levi's Stadium in Week 6—the marquee trap game on the 49ers' 2026 schedule. The NFL offseason's most-watched soap opera is building toward a Monday night in October. If Brandon Aiyuk's standoff with the Niners... -
49ers' George Kittle fires back at critics claiming Kyle Shanahan is on the hot seat
Kyle Shanahan delivered one of the most impressive coaching performances of his career last season, guiding the San Francisco 49ers to the playoffs despite a roster ravaged by injuries. Now entering his 10th season as the 49ers' head coach, Shanahan has led the franchise to... -
49ers announce running back roster moves
The San Francisco 49ers have signed running back Sincere McCormick to a one-year deal. To make room on the roster, the team waived running back Jordan Mims. The 49ers Communications staff provided the following rundown. McCormick (5-8, 204) originally entered the NFL after... -
Florio: Reporting to 49ers training camp could boost Brandon Aiyuk's leverage
The rift between the San Francisco 49ers and wide receiver Brandon Aiyuk appears significant, with the receiver recently taking multiple public shots at the organization. The 49ers have already voided a portion of the guaranteed money in the four-year, $120 million contract...