RELATED
"49ers are waiving former second-round pick Drake Jackson with a failed physical designation, per source," Schefter wrote on social media. "Jackson is still rehabbing a knee injury but is expected to be cleared by the start of training camp."
Jackson was entering the final year of his rookie contract and carried a $1.9 million cap hit in 2025. Over 23 career appearances, the defensive lineman recorded just six sacks. With his departure, none of the 49ers' top draft picks from 2020 to 2022—Jackson, quarterback Trey Lance, and defensive tackle Javon Kinlaw—remain on the roster.
Jackson struggled to meet expectations after being drafted. He last appeared in a game during the 2023 season, playing in eight contests before landing on injured reserve. He then spent the entire 2024 season on the physically unable to perform (PUP) list following the previous year's knee surgery.
In February, general manager John Lynch spoke candidly about Jackson's recovery.
"It's been a tough injury ... those quad tendon repairs," Lynch explained. "And that's why you've got to really think long and hard before you have that [surgery] because it doesn't just make it go away. ... I guess Drake has had—not setbacks—but just trouble coming back from it.
"So, it's not been the most encouraging thing. Hopefully, it takes a turn for the positive because we've seen, Drake, when he's healthy, he can be a real effective player for us."
Related News
More San Francisco 49ers News
-
49ers tabbed as best fit for former Eagles, Steelers O-lineman
The San Francisco 49ers are widely expected to address their offensive line this offseason, with many analysts projecting the team to invest a premium draft pick in the unit. However, ESPN analyst Matt Bowen believes part of the solution could come through NFL free... -
Where 49ers QB Brock Purdy landed in PFF's top 101 players of 2025
San Francisco 49ers quarterback Brock Purdy appeared in just nine games during the 2025 NFL season, missing eight contests due to a turf toe injury suffered in Week 1. Still, the former final pick of the 2022 NFL Draft did more than enough to earn recognition from Pro Football... -
Tyreek Hill to the 49ers? San Francisco named a top fit for All-Pro WR
The Miami Dolphins have moved on from wide receiver Tyreek Hill, releasing the veteran nearly five months after he suffered a significant knee injury. Hill underwent surgery to repair the damage, and his agent, Drew Rosenhaus, has previously stated that the goal is for the star... -
Where 49ers OT Colton McKivitz landed in PFF's top 101 players of 2025
What a difference a season made for San Francisco 49ers right tackle Colton McKivitz. The veteran offensive lineman made his debut on Pro Football Focus' (PFF) list of the top 101 players of the 2025 NFL season, checking in at No. 63 — notably ahead of quarterback Brock...