The San Francisco 49ers will take on the Arizona Cardinals at State Farm Stadium on Sunday, January 5. Kickoff is scheduled for 1:25 p.m. PT, with FOX handling the broadcast.
While both teams have been eliminated from playoff contention, this NFC West matchup offers a chance to finish the season on a positive note. It's an opportunity for each organization to defeat a divisional rival and build some momentum heading into the offseason.
Below is the complete Week 18 schedule:
| Saturday, January 4, 2025 | Time (PT) | Network |
| Cleveland Browns at Baltimore Ravens | 1:30 p.m. | ESPN/ABC |
| Cincinnati Bengals at Pittsburgh Steelers | 5:00 p.m. | ESPN/ABC |
| Sunday, January 5, 2025 | Time (PT) | Network |
| Carolina Panthers at Atlanta Falcons | 10:00 a.m. | CBS |
| Washington Commanders at Dallas Cowboys | 10:00 a.m. | FOX |
| Chicago Bears at Green Bay Packers | 10:00 a.m. | FOX |
| Jacksonville Jaguars at Indianapolis Colts | 10:00 a.m. | FOX |
| Buffalo Bills at New England Patriots | 10:00 a.m. | CBS |
| New York Giants at Philadelphia Eagles | 10:00 a.m. | CBS |
| New Orleans Saints at Tampa Bay Buccaneers | 10:00 a.m. | FOX |
| Houston Texans at Tennessee Titans | 10:00 a.m. | CBS |
| San Francisco 49ers at Arizona Cardinals | 1:25 p.m. | FOX |
| Kansas City Chiefs at Denver Broncos | 1:25 p.m. | CBS |
| Los Angeles Chargers at Las Vegas Raiders | 1:25 p.m. | CBS |
| Seattle Seahawks at Los Angeles Rams | 1:25 p.m. | FOX |
| Miami Dolphins at New York Jets | 1:25 p.m. | FOX |
| Minnesota Vikings at Detroit Lions | 5:20 p.m. | NBC |
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