Each week, 49ers Webzone staff members participate in the NFL Pick 'em contest, predicting the outcome of every NFL game. For Week 7, only two of the six staff participants have picked the 49ers to beat the Chiefs.
As for the fans in our NFL Pick 'Em contest, a season-low 61 percent have predicted a 49ers victory, as of this post.
Most One-Sided Matchup: Panthers at Commanders
Among all Week 7 games, the matchup between the Carolina Panthers and the Washington Commanders has the most lopsided predictions, with 99 percent expecting the Commanders to secure the win.
Most Competitive Matchup: Texans at Packers
The closest matchup in terms of predictions is Sunday's game between the Houston Texans and the Green Bay Packers, with 54 percent favoring the Packers to emerge victorious.
Week 7 NFL Matchups
Below is a breakdown of all 14 remaining matchups in this week's slate of NFL games.
| Picks | Away | Home | Picks |
|---|---|---|---|
|
17%
|
Patriots
|
Jaguars
|
83%
|
|
13%
|
Seahawks
|
Falcons
|
87%
|
|
2%
|
Titans
|
Bills
|
98%
|
|
89%
|
Bengals
|
Browns
|
11%
|
|
46%
|
Texans
|
Packers
|
54%
|
|
18%
|
Dolphins
|
Colts
|
82%
|
|
62%
|
Lions
|
Vikings
|
38%
|
|
87%
|
Eagles
|
Giants
|
13%
|
|
10%
|
Raiders
|
Rams
|
90%
|
|
1%
|
Panthers
|
Commanders
|
99%
|
|
39%
|
Chiefs
|
49ers
|
61%
|
|
44%
|
Jets
|
Steelers
|
56%
|
|
76%
|
Ravens
|
Buccaneers
|
24%
|
|
78%
|
Chargers
|
Cardinals
|
22%
|
More San Francisco 49ers News
-
49ers' George Kittle shares update on Week 1 availability amid Achilles recovery
San Francisco 49ers tight end George Kittle suffered a torn Achilles during the Wild Card playoff victory over the Philadelphia Eagles, forcing him to miss the following week's Divisional Round matchup against the Seattle Seahawks. Initially, the injury was viewed as one that... -
49ers' most important position battle features Ricky Pearsall
Left guard is expected to be one of the most closely watched position battles for the San Francisco 49ers during training camp. However, offensive line competitions rarely generate the same level of attention as battles at the skill positions. In a recent article identifying... -
Where does 49ers' Mac Jones rank among NFL backup QBs by trade value?
Mac Jones saved the San Francisco 49ers' season in 2025. That wasn't a statement any fan expected to hear before last season began. But it happened. And it's not an overreaction. Starting QB Brock Purdy missed eight games in 2025. And Jones filled in admirably, going 5-3, and... -
USA Today predicts 49ers record for 2026
Last season, the San Francisco 49ers finished with an impressive 12-5 record, despite many injuries to key players. Some injuries, like those to Brock Purdy, George Kittle, and Ricky Pearsall, lasted multiple weeks. But there were more devastating ones, like the season-ending...